Articles & Webinars

A cell contains thousands of lipids. Lipidomics reports the precise lipid composition of a sample to fuel research and progress in all biology related fields.

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The title image of the Lipidomics Webinar "Role of Lipids in Central Nervous System Regeneration" with Mikael Simons.
Upcoming webinar The Lipidomics Webinar | Mikael Simons

Failure of regeneration capacity limits the restoration of nervous system functionality in demyelinating diseases.

The title image of the Lipidomics Webinar "The Composition, Organization and Function of Mammalian Plasma Membranes" with Ilya Levental.
Webinar The Lipidomics Webinar | Ilya Levental

The plasma membrane is the interface between a cell and its environment. Its processing tasks must be tightly regulated.

A photo of broken wires which are fixed with band-aid.
Article Technical University of Munich

Remyelination requires orchestrated lipid droplets formation and cholesterol esterification by microglia.

A computer render graphic showing a dendritic cell presenting an antigen to a T cell.
Article University College London

Activation of LXR in T helper cells alters lipid metabolism, reduces membrane order, and modifies the immune response.

The title image of the Lipidomics Webinar "What Have Lipids to Do With the Worst Pandemic Ever?" with Kai Simons.
Webinar The Lipidomics Webinar | Kai Simons

Dysmetabolism is rapidly spreading worldwide, giving rise to obesity and other diseases. Yet, there is no diagnostic test.

An artistic image of a human face made from blocks.
Article Lipotype

Multiomics analyses of well-studied diseases can reveal molecular pathways, identify biomarkers, and improve predictive models.

The title image of the Lipidomics Webinar "Shotgun Lipidomics of Tissue Biopsies" with Andrej Shevchenko.
Webinar The Lipidomics Webinar | Andrej Shevchenko

Direct analysis of tissue biopsies could be in a better position to elucidate pathophysiological mechanisms than liquid biopsies.

A medical model of the female reproductive organ system.
Article China Medical University Hospital

LDLR expression influences ovarian cancer cells’ sensitivity to platinum-based chemotherapy.

The title image of the Lipidomics Webinar #005 "How to Yeast Lipidomics Research" with Christian Klose.
Webinar The Lipidomics Webinar | Christian Klose

Yeast is a powerful model system for cell and molecular biology research. What should be considered when conducting yeast lipidomics?

A computer render of a mitochondrium.
Article Albert-Ludwigs-Universität Freiburg

The mtUPR in yeast exhibits an initial increase in protein import, which is accompanied by cardiolipin synthesis and remodeling.

A photo of colorful mosaic.
Article Utrecht University

Yeast adapts to the absence of phosphatidylcholine by changing lipid composition to restore membrane fluidity.

The title image of the Lipidomics Webinar #004 "How to Make Sense of Lipidomics Data?" with Mathias Gerl.
Webinar The Lipidomics Webinar | Mathias Gerl

The amount and complexity of lipidomics data sets can be intimidating initially – but this does not need to be the case.

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Article University Hospital Carl Gustav Carus

The plasma lipidome in anorexia patients before and after refeeding therapy exhibits dysregulated lipid metabolism.

A photo of a man eating cupcakes from a fridge at night.
Article German Institute of Human Nutrition

The plasma lipid profile depends on meal timing and composition and is associated with insulin sensitivity.

The title image of the Lipidomics Webinar #003 "Why Cohort Studies Must Run Lipidomics" with Christian Klose.
Webinar The Lipidomics Webinar | Christian Klose

Cohort studies frequently rely on omics technologies but benefit only if the data are of high quality and reproducible.

A scientific computer render of vascularized cancer tissue.
Article The University of Hong Kong

The enzyme PTPMT1, which synthesizes the mitochondrial lipid cardiolipin, helps cancer cells adapt to hypoxia.

The title image of the Lipidomics Webinar #002 "Are Mouse and Lipidomics the Perfect Match?" with Christian Klose.
Webinar The Lipidomics Webinar | Christian Klose

The detailed mouse lipidomics atlas facilitates experimental design and interpretation in mouse studies.

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Article Nestlé Health Science

Multiomics analyses with lipidomics reveal molecular pathways in Alzheimer’s disease to improve predictive power.

A computer render of three women ranging from normal weight to obesity.
Article Finnish Institute for Health and Welfare

Metabolic indicators in the plasma lipidome can classify obesity status more accurately than standard metrics.

The title image of the Lipidomics Webinar #001 "Lipids Are Cool Again" with Kai Simons.
Webinar The Lipidomics Webinar | Kai Simons

The obesity pandemic threatens lipid metabolism homeostasis which is vital for health. The return of lipids can combat this.

A close up photo of two people's lower half of the face.
Article Wrocław Medical University

Skin lipid composition impacts skin health and can be studied via lipidomics but sex, age and, sample depth affect the data.

A computer render of the human heart.
Article Charité Universitätsmedizin

Heart failure changes lipid metabolism in cardiac tissue of mice. The altered lipid profile can be confirmed in human plasma.

A close-up photo of an insulin syringe for type 1 diabetes treatment.
Article Ludwig-Maximilians-Universität München

Combined transcriptomic, proteomic, lipidomic, & metabolomic analyses can characterize the molecular basis of diabetes.

A computer render of exosomes entering a cell.
Article Roche

Exosomes may be useful for targeted drug delivery. Proteomic & lipidomic characterization are required for this goal.

An abstract computer render of the anatomy of the breast of a female human.
Article UTHealth

Breast cancer phospholipid metabolism is a powerful target for new therapies, especially against triple-negative breast cancer.

A tinted photo of a head with golden glitter sprinkled on the right side of the face.
Article DZNE

The brain of mammals is the second-most lipid-rich organ. Lipid analysis of neural cells helps understand its complex structure.

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Article DZNE

Diagnosing multiple sclerosis is difficult. Lipid markers can support diagnosis and treatment of the neuroinflammatory disease.

A red light LED model of the heart mounted on a black surface.
Article Institute for Molecular Medicine Finland

A population health study examined the relationships between genotypes, the plasma lipidome, and cardiovascular diseases.

A close-up photo of a canister of moisturizer balm.
Article DSM

Skin biology is central to develop reliable moisturizers, but molecular analysis of the skin has been lacking.

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Article Helmholtz Centre for Infection Research

The development of new antibiotics alone is not believed to stop multi resistant bacteria. A new strategy is emerging.

A syringe filled with a red fluid.
Article Université Libre de Bruxelles

Adjuvants are added to vaccines to boost their efficiency, but the underlying molecular mechanisms used to be poorly understood.

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