Articles & Webinars

A cell contains thousands of lipids. Lipidomics reports the precise lipid composition of a sample to fuel research and progress in all biology related fields.

Filter content by tags
Lipidomics data analysis: OPLS-DA
Article Lipotype

Try OPLS-DA when a PCA score plot cannot tell differences between different sample groups.

Upcoming webinar The Lipidomics Webinar | Olya Vvedenskaya

Lipidomics helps researchers cover aspects from fundamental processes to applications to disease development and treatment.

A computer render of a lipid droplet surface.
Article KRICT

The structural flexibility of lipids affects their migration into lipid droplets.

A graphic with red and blue nodes connected with lines.
Article Lipotype

Enrichment analysis helps to identify the most prominent features in lipidomics datasets.

An image depicting a plant-shaped liquid
Article Medical University of Lublin

Camelina, flax, and hemp oils lipidomics.

Ganglioside lipidomics in CNS developmental myelination
Article DZNE

Researchers developed a method to quantify the full ganglioside lipidome in CNS during various developmental stages.

Group of colorful cubes in a row, blue background. Abstract illustration, 3d render.
Article Lipotype

Imputation helps to deal with missing values in lipidomics datasets.

Webinar The Lipidomics Webinar | Mathias Gerl

Knowledge about statistical and data analysis methods tailored for lipid data is key to successful lipidomics studies.

Starvation and lipid metabolism. TANGO2 plays a role in lipid metabolism and affects cellular organization during starvation.
Article Centre for Genomic Regulation

TANGO2 plays a role in lipid metabolism and affects cellular organization during starvation.

Phospholipidomics of a murine eye
Article University of Florida

Phosphoinositide lipids show area-specific distribution in the rods of a mouse retina.

A photo of a white mouse eating a cashew nut.
Article Nestlé Health Science

Age-related gut microbiome changes are reflected in serum lipidome.

A hand showing heart sign with fingers
Article Lipotype

Lipidomics analysis of stratum corneum is essential in dermatology research and product development.

The title image of the Lipidomics Webinar "Navigating Cardiovascular Diseases: Insights from Lipidomics" with Olya Vvedenskaya.
Webinar The Lipidomics Webinar | Olya Vvedenskaya

Cardiovascular diseases are linked to changes in lipid metabolism. Lipidomics helps assess cardiovascular disease risk.

Lipidomics of extracellular vesicles subtype
Article University of Basel, Pharmaceutical Sciences

Lipidomics analysis supports the preparation and analysis of nano plasma membrane vesicles (nPMVs).

A close-up photo of oil forming droplets.
Article University of Virginia

PUFAs coming from diet incorporate into the plasma membrane and affect its biophysical properties.

The title image of the Lipidomics Webinar "Exploring Skin Lipidomics & Ceramide Analysis for Skin Research" with Veronika Piskovatska.
Webinar The Lipidomics Webinar | Veronika Piskovatska

Skin health and disease is closely related to lipid composition and function in different skin structures.

A photo of a person applying a cream on their shoulder.
Article Pierre Fabre

A glycerol/petrolatum-based emollient cream improves ceramide balance and strengthens the skin barrier function.

Ferroptosis article title image.
Article Fox Chase Cancer Center

Conjugated linoleates can act as ferroptosis inducers by promoting lipid peroxidation and cancer cell death.

Lipidomics Of Cardiovascular Diseases
Article Lipotype

Lipidomics analysis of blood plasma helps to predict and differentiate various cardiovascular diseases.

Lipid metabolism gene editing is visualized with the hand holding a part of a DNA with the forceps
Article MPI-CBG

CRISPR/Cas9-based gene knockouts allow for a better understanding of lipid metabolic pathways.

Healthy Obesity Title image depicting two people
Article Lund University

Lipid profiling differentiates between metabolically healthy and unhealthy obesity.

Lipases Title image features the shape of a brain
Article Harvard Medical School

Regulating fatty acid metabolism using lipases could be beneficial in Parkinson’s disease treatment.

The image of a person and red-green-blue graphs infront of the person.
Article TWINCORE

Lipidomics risk score allows to accurately measure the risk of diabetes and cardiovascular disease development

An photo of a dozen of zebrafishes in the water
Article University of Michigan

Temperature conditions affect the lipid composition of giant plasma membrane vesicles obtained from cells.

Article Lipotype

Endoplasmic reticulum stress is a process that is involved in the development of many diseases.

Lipid Profiles Of Cardiovascular And Inflammatory Diseases
Article iNOVA4Health

Plasma lipidomics analysis is a promising tool for a differential diagnosis of various atherosclerosis-related vascular diseases.

Computer graphics depicting two kidneys on a grey background
Article Heidelberg University Hospital

Modifying dietary fatty acids composition may protect the kidney in patients with diabetes.

The title image of the Lipidomics Webinar "Role of Lipids in Central Nervous System Regeneration" with Mikael Simons.
Webinar The Lipidomics Webinar | Mikael Simons

Failure of regeneration capacity limits the restoration of nervous system functionality in demyelinating diseases.

A close photo of hands where the person applying creme to hands.
Article Unilever

Application of a moisturizing body lotion to dry skin improves barrier properties and alters ceramide profile and skin microbiome.

The title image of the Lipidomics Webinar "The Composition, Organization and Function of Mammalian Plasma Membranes" with Ilya Levental.
Webinar The Lipidomics Webinar | Ilya Levental

The plasma membrane is the interface between a cell and its environment. Its processing tasks must be tightly regulated.

A photo of broken wires which are fixed with band-aid.
Article Technical University of Munich

Remyelination requires orchestrated lipid droplets formation and cholesterol esterification by microglia.

A computer render graphic showing a dendritic cell presenting an antigen to a T cell.
Article University College London

Activation of LXR in T helper cells alters lipid metabolism, reduces membrane order, and modifies the immune response.

The title image of the Lipidomics Webinar "What Have Lipids to Do With the Worst Pandemic Ever?" with Kai Simons.
Webinar The Lipidomics Webinar | Kai Simons

Dysmetabolism is rapidly spreading worldwide, giving rise to obesity and other diseases. Yet, there is no diagnostic test.

An artistic image of a human face made from blocks.
Article Lipotype

Multiomics analyses of well-studied diseases can reveal molecular pathways, identify biomarkers, and improve predictive models.

The title image of the Lipidomics Webinar "Shotgun Lipidomics of Tissue Biopsies" with Andrej Shevchenko.
Webinar The Lipidomics Webinar | Andrej Shevchenko

Direct analysis of tissue biopsies could be in a better position to elucidate pathophysiological mechanisms than liquid biopsies.

A medical model of the female reproductive organ system.
Article China Medical University Hospital

LDLR expression influences ovarian cancer cells’ sensitivity to platinum-based chemotherapy.

The title image of the Lipidomics Webinar #005 "How to Yeast Lipidomics Research" with Christian Klose.
Webinar The Lipidomics Webinar | Christian Klose

Yeast is a powerful model system for cell and molecular biology research. What should be considered when conducting yeast lipidomics?

A computer render of a mitochondrium.
Article Albert-Ludwigs-Universität Freiburg

The mtUPR in yeast exhibits an initial increase in protein import, which is accompanied by cardiolipin synthesis and remodeling.

A photo of colorful mosaic.
Article Utrecht University

Yeast adapts to the absence of phosphatidylcholine by changing lipid composition to restore membrane fluidity.

The title image of the Lipidomics Webinar #004 "How to Make Sense of Lipidomics Data?" with Mathias Gerl.
Webinar The Lipidomics Webinar | Mathias Gerl

The amount and complexity of lipidomics data sets can be intimidating initially – but this does not need to be the case.

A photo of a person mirrored by a puddle.
Article University Hospital Carl Gustav Carus

The plasma lipidome in anorexia patients before and after refeeding therapy exhibits dysregulated lipid metabolism.

A photo of a man eating cupcakes from a fridge at night.
Article German Institute of Human Nutrition

The plasma lipid profile depends on meal timing and composition and is associated with insulin sensitivity.

The title image of the Lipidomics Webinar #003 "Why Cohort Studies Must Run Lipidomics" with Christian Klose.
Webinar The Lipidomics Webinar | Christian Klose

Cohort studies frequently rely on omics technologies but benefit only if the data are of high quality and reproducible.

A scientific computer render of vascularized cancer tissue.
Article The University of Hong Kong

The enzyme PTPMT1, which synthesizes the mitochondrial lipid cardiolipin, helps cancer cells adapt to hypoxia.

The title image of the Lipidomics Webinar #002 "Are Mouse and Lipidomics the Perfect Match?" with Christian Klose.
Webinar The Lipidomics Webinar | Christian Klose

The detailed mouse lipidomics atlas facilitates experimental design and interpretation in mouse studies.

An artistic image of a head filled with smoke.
Article Nestlé Health Science

Multiomics analyses with lipidomics reveal molecular pathways in Alzheimer’s disease to improve predictive power.

A computer render of three women ranging from normal weight to obesity.
Article Finnish Institute for Health and Welfare

Metabolic indicators in the plasma lipidome can classify obesity status more accurately than standard metrics.

The title image of the Lipidomics Webinar #001 "Lipids Are Cool Again" with Kai Simons.
Webinar The Lipidomics Webinar | Kai Simons

The obesity pandemic threatens lipid metabolism homeostasis which is vital for health. The return of lipids can combat this.

A close photo of two faces of different age.
Article Wrocław Medical University

Skin lipid composition impacts skin health and can be studied via lipidomics but sex, age and, sample depth affect the data.

A computer render of the human heart.
Article Charité Universitätsmedizin

Heart failure changes lipid metabolism in cardiac tissue of mice. The altered lipid profile can be confirmed in human plasma.

A close-up photo of an insulin syringe for type 1 diabetes treatment.
Article Ludwig-Maximilians-Universität München

Combined transcriptomic, proteomic, lipidomic, & metabolomic analyses can characterize the molecular basis of diabetes.

A computer render of exosomes entering a cell.
Article Roche

Exosomes may be useful for targeted drug delivery. Proteomic & lipidomic characterization are required for this goal.

An abstract computer render of the anatomy of the breast of a female human.
Article UTHealth

Breast cancer phospholipid metabolism is a powerful target for new therapies, especially against triple-negative breast cancer.

A tinted photo of a head with golden glitter sprinkled on the right side of the face.
Article DZNE

The brain of mammals is the second-most lipid-rich organ. Lipid analysis of neural cells helps understand its complex structure.

An abstract depiction of an antique bust with a reality warping slash hitting the head of the bust.
Article DZNE

Diagnosing multiple sclerosis is difficult. Lipid markers can support diagnosis and treatment of the neuroinflammatory disease.

A red light LED model of the heart mounted on a black surface.
Article Institute for Molecular Medicine Finland

A population health study examined the relationships between genotypes, the plasma lipidome, and cardiovascular diseases.

A close up photo of two people's lower half of the face.
Article DSM

Skin biology is central to develop reliable moisturizers, but molecular analysis of the skin has been lacking.

A selection of different pills on a yellow background.
Article Helmholtz Centre for Infection Research

The development of new antibiotics alone is not believed to stop multi resistant bacteria. A new strategy is emerging.

A syringe filled with a red fluid.
Article Université Libre de Bruxelles

Adjuvants are added to vaccines to boost their efficiency, but the underlying molecular mechanisms used to be poorly understood.

Happy Researchers, Happy Life!

But they can tell you more. Access the Lipidomics Resource Center to study all publications with Lipotype technology.

Lipidomics Resource Center