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We provide MS-based lipid analysis of Desm in a variety of sample types and deliver results in six or less weeks.


Sterol Lipids
Lipid Category
Lipid Class

About the structure and biological function of Desm

Structure. Desmosterol (cholest-5,24-dien-3β-ol, or Desm) belongs to the group of cholesterol lipids within the sterol lipids category. Its structure consists of the steroid structure, four linked hydrocarbon rings, to which a hydrocarbon tail containing a double bond is linked at one end of the steroid and a hydroxyl group is linked to the other end.

Function. Desmosterol is a key intermediate in the Bloch pathway biosynthesis of cholesterol. Desm impacts diverse immunological processes such as inflammatory stress response, macrophage activation, or B cell differentiation. Accumulation of desmosterol can activate the liver X receptor and therefore affect lipid metabolism regulation. This strategy is currently being explored for treating cardiovascular diseases, diabetes, multiple sclerosis, and other disorders.

Desm lipidomics analysis with

Structural detailsclass level
Variants identified 1
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Delivery time6 weeks
Lipidomics datapmol & mol%


Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

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    Aldeyra Therapeutics
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    Friedrich Miescher Institute
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    KU Leuven
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    DSM Skin Biology
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    Yale University
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    University of Alberta
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    University of Virginia
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    University College London
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