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Sphinganine-phosphate

We provide MS-based lipid analysis of dhSphP sphingolipids in a variety of sample types and deliver results in six or less weeks.

Details

Sphingolipids
Lipid Category
Sphingoid Bases
Lipid Group

About the structure and biological function of dhSphP

Structure. Sphinganine-phosphates (dihydrosphingosine-phosphates, sphinganine-1-phosphates, or dhSphP) belong to the group of sphingoid bases within the sphingolipids. Their structure consists of an amino alcohol with a saturated hydrocarbon chain linked to a phosphate molecule.

Function. Little is known about the function of sphinganine-phosphates. However, they have been implicated in the protection of kidney and liver after hepatic ischemia and reperfusion, a major complication after liver transplantation. Futher, sphinganine-phosphate levels may serve as a biomarker for fumonisin exposure, a group of mycotoxins produced by fungi of the genus fusarium.

dhSphP lipidomics analysis with
Lipotype

Structural detailsmolecular species
Variants identified < 10
Approachtargeted
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Quantificationyes
Delivery time6 weeks
Lipidomics datapmol & mol%
Figuresincluded

EXAMPLE STRUCTURE
dhSphP

An example for the molecular structure of sphinganine-phosphate, specifically SPBP 18:0;O2.

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