Structure. Non-hydroxy-fatty acid [N] phytosphingosine [P] ceramides (CER[NP], or NP) belong to the group of ceramide lipids within the sphingolipids. Their structure consists of a sphingoid base, specifically phytosphingosine, and a fatty acid, which is a non-hydroxy fatty acid. The fatty acid can be of variable length, hydroxylated, and contain double bonds.
Function. The function of non-hydroxy-phytosphingosines is tightly linked to skin health where they serve structural and signaling roles. NP ceramides are involved in the formation of the epidermal barrier which protects against the environment and prevents trans-epidermal water loss. Skin ceramide imbalances can lead or contribute to the development of skin conditions. Increased NP levels are associated with psoriasis. Further, NP ceramides are decreased in Albino African skin.
Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.
★★★★★
Thank you once again. The timing is extremely helpful to us.
Susan Macdonald
Aldeyra Therapeutics
Thank you very much. The results look fantastic!
Stan Neufeld
Friedrich Miescher Institute
The high-speed turn around when under revision really helped us!
Rose E Goodchild
KU Leuven
We highly appreciate the personal support and consultation.
Rainer Voegeli
DSM Skin Biology
We have been quite impressed. The results clearly indicate a difference.
Pietro De Camilli
Yale University
Cooperating with Lipotype, I enjoy custom packages and great support!
Olga Ramich
DIfE
After moving from one continent to another, I still prefer Lipotype!
Julie Jacquemyn
University of Alberta
Thank you very much for my new and shiny lipidomics data set!
Ilya Levental
University of Virginia
Lipotype Lipidomics is instrumental to our studies of membranes.
Christopher J Stefan
University College London
Lipotype is truly dedicated to supporting scientists in their research.
Anonymous
Anonymous
Contact Lipotype
You are currently viewing a placeholder content from OpenStreetMap. To access the actual content, click the button below. Please note that doing so will share data with third-party providers.
