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Lyso-phosphatidyl­serine

We provide MS-based lipid analysis of LPS phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of LPS

Structure. Lyso-phosphatidyl-serines (LysoPtdSer, LysoPS, or LPS) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphoserine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Lyso-phosphatidyl-serines are mediators in many biological processes, especially those of the immune system of animals. LPS levels are elevated by various inflammatory stimuli and after injury, where it can transmit the information to other cells. Thus they contribute to the resolution of inflammation. Yet, certain LPS lipids have pro-inflammatory reactions. Further, LPS metabolism aberrations are linked to cancers, night blindness, and PHARC, a genetic neurological disorder.

LPS lipidomics analysis with
Lipotype

Structural detailsspecies level
Variants identified > 100
Approachuntargeted
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Extended includes:
LPA, LPC, LPE, LPG, LPI, LPS, PC O-, PE O-, LPC O-, LPE O-, CL, Cer, HexCer

EXAMPLE STRUCTURE
LPS

An example for the molecular structure of lyso-phosphatidylserine, specifically LPS 16:1;0.

EXAMPLE
LPS 16:1;0

An example for the molecular structure of lyso-phosphatidylserine, specifically LPS 16:1;0.

ABOUT LIPOTYPE

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