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Oxidized Fatty Aldehyde

We provide MS-based lipid analysis of oxiFAL fatty acyls in a variety of sample types and deliver results in six or less weeks.


Fatty Acyls
Lipid Category
Fatty Aldehydes
Lipid Group

About the structure and biological function of oxiFAL

Structure. Oxidized fatty aldehydes (oxiFAL) belong to the group of fatty aldehydes within the fatty acyls. Their structure is based on a fatty acid where the carboxyl group has been replaced with an aldehyde group. The hydrocarbon chain of oxiFALs further encompasses multiple oxygen containing substituents such as hydroxy and epoxy groups, and may feature one or multiple double bonds.

Function. Oxidized fatty aldehydes with six or nine carbon atoms such as 4-HNE and 4-HHE are the main volatile autooxidation products from the n-6 and n-3 families of polyunsaturated fatty acids. They are considered cytotoxic in cells which are not equipped to metabolize them as they influence cell viability and function. As such, oxiFALs are involved in various diseases, including diabetes, immunological, and age-related diseases.

oxiFAL lipidomics analysis with

Structural detailsmolecular species
Variants identified < 10
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Delivery time6 weeks
Lipidomics datapmol & mol%


An example for the molecular structure of oxiFAL 4-HNE.


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