About the structure and biological function of GlcSph
Structure. Glucosylsphingosines (glucosyl-sphing-4-enines, glucosphingosines, lyso-Gb1, or GlcSph) belong to the group of sphingoid bases within the sphingolipids. Their structure consists of an amino alcohol with a monounsaturated hydrocarbon chain linked to a glucose molecule.
Function. The biological role of glucosylsphingosines has been mostly associated with Gaucher disease, a rare genetic disorder and lysosomal storage disease during which GlcSph accumulates among other sphingolipids. Further, they have been associated with tumor progression in melanoma and glusosylsphingosines are also associated with activating an itch-scratch response pathway in atopic dermatitis.
Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.
★★★★★
Thank you once again. The timing is extremely helpful to us.
Susan Macdonald
Aldeyra Therapeutics
Thank you very much. The results look fantastic!
Stan Neufeld
Friedrich Miescher Institute
The high-speed turn around when under revision really helped us!
Rose E Goodchild
KU Leuven
We highly appreciate the personal support and consultation.
Rainer Voegeli
DSM Skin Biology
We have been quite impressed. The results clearly indicate a difference.
Pietro De Camilli
Yale University
Cooperating with Lipotype, I enjoy custom packages and great support!
Olga Ramich
DIfE
After moving from one continent to another, I still prefer Lipotype!
Julie Jacquemyn
University of Alberta
Thank you very much for my new and shiny lipidomics data set!
Ilya Levental
University of Virginia
Lipotype Lipidomics is instrumental to our studies of membranes.
Christopher J Stefan
University College London
Lipotype is truly dedicated to supporting scientists in their research.
Anonymous
Anonymous
Contact Lipotype
You are currently viewing a placeholder content from OpenStreetMap. To access the actual content, click the button below. Please note that doing so will share data with third-party providers.