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We provide MS-based lipid analysis of Lath in a variety of sample types and deliver results in six or less weeks.


Sterol Lipids
Lipid Category
Lipid Class

About the structure and biological function of Lath

Structure. Lathosterol (cholest-7-en-3β-ol, or Lath) belongs to the group of cholesterol lipids within the sterol lipids category. Its structure consists of the steroid structure, four linked hydrocarbon rings, to which a hydrocarbon tail is linked at one end of the steroid structure and a hydroxyl group is linked to the other end. Lathosterol differs from cholesterol by the position of a double bond in the steroid structure.

Function. Lathosterol plays a significant role in the cholesterol biosynthesis serving as a cholesterol precursor in Kandutsch-Russell pathway. In human serum samples, lath levels correlate with cholesterol levels and may thus serve as biomarkers for the success of statin therapy. Further, alterations in lathosterol levels have been observed in Huntington’s disease, several types of leukodystrophy, and lathosterolosis.

Lath lipidomics analysis with

Structural detailsclass level
Variants identified 1
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Delivery time6 weeks
Lipidomics datapmol & mol%


Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

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    Aldeyra Therapeutics
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    Friedrich Miescher Institute
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    KU Leuven
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    DSM Skin Biology
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    University of Alberta
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    University of Virginia
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    University College London
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