About the structure and biological function of oxiOTrE
Structure. Oxidized octadecatrienoic acids (oxiOTrE) belong to the group of octadecanoids within the fatty acyls. Their structure is based on octadecanoic acid, an eighteen carbon atoms long hydrocarbon chain with a carboxyl group. The chain contains three double bonds, from which their name derives. OxiOTrE may further encompass multiple hydroxy groups as well as other oxygen containing substituents.
Function. Oxidized octadecatrienoic acids are involved in the regulation of oxidative stress and inflammation. They possess inhibitory effects on platelet aggregation and anti-inflammatory properties. Further, oxiOTrE species have been shown to have cardioprotective properties. In plants, bacteria, and fungi, oxiOTrE are involved in the biosynthesis of compounds related to environmental stress responses.