Sulfoglycosphingolipids
Details
Lipid Category
Lipid Group
About the structure and biological function of Sulfoglycosphingolipids
Structure. Sulfoglycosphingolipids (or glycosphingolipid sulfates) belong to the sphingolipids. Their structure consists of a ceramide backbone linked to a sulfated saccharide “head” group, such as a sulfated mono-, di-, or oligosaccharide. The ceramide backbone of sulfoglycosphingolipids contains a hydrocarbon chain termed long-chain base; one fatty acid is linked to the ceramide.
Function. Sulfoglycosphingolipids may primarily be found in animals and are involved in a plentitude of cellular processes. Many of these are consequences of sulfoglycosphingolipids binding to specific proteins and thus contributing to, for example, platelet aggregation, folding of proinsulin, and inflammation initiation.
Sulfogalactosylceramides (Sulf) are the most prominent sulfoglycosphingolipids. They are an important structural and functional constituent of myelin, the insulating layer that wraps around nerves. Many further types of sulfoglycosphingolipids, such as sulfolactosylceramides, have been discovered primarily in animal tissues, where they serve specific regional functions.
Sulfoglycosphingolipids lipidomics analysis with Lipotype
| Covered classes | 1 |
| Approach | untargeted |
| Method | mass spectrometry |
| Device | Q Exactive Orbitrap (280.000 Res) |
| Quantification | yes |
| Delivery time | 2-6 weeks |
| Lipidomics data | pmol & mol% |
CORE STRUCTURE
Sulfoglycosphingolipids
Interested in
Sulfoglycosphingolipids
analysis?
Lipid Navigator
Request Analysis
You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!