About the structure and biological function of Sulfoglycosphingolipids
Structure. Sulfoglycosphingolipids (or glycosphingolipid sulfates) belong to the sphingolipids. Their structure consists of a ceramide backbone linked to a sulfated saccharide “head” group, such as a sulfated mono-, di-, or oligosaccharide. The ceramide backbone of sulfoglycosphingolipids contains a hydrocarbon chain termed long-chain base; one fatty acid is linked to the ceramide.
Function. Sulfoglycosphingolipids may primarily be found in animals and are involved in a plentitude of cellular processes. Many of these are consequences of sulfoglycosphingolipids binding to specific proteins and thus contributing to, for example, platelet aggregation, folding of proinsulin, and inflammation initiation.
Sulfogalactosylceramides (Sulf) are the most prominent sulfoglycosphingolipids. They are an important structural and functional constituent of myelin, the insulating layer that wraps around nerves. Many further types of sulfoglycosphingolipids, such as sulfolactosylceramides, have been discovered primarily in animal tissues, where they serve specific regional functions.
Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.
★★★★★
Thank you once again. The timing is extremely helpful to us.
Susan Macdonald
Aldeyra Therapeutics
Thank you very much. The results look fantastic!
Stan Neufeld
Friedrich Miescher Institute
The high-speed turn around when under revision really helped us!
Rose E Goodchild
KU Leuven
We highly appreciate the personal support and consultation.
Rainer Voegeli
DSM Skin Biology
We have been quite impressed. The results clearly indicate a difference.
Pietro De Camilli
Yale University
Cooperating with Lipotype, I enjoy custom packages and great support!
Olga Ramich
DIfE
After moving from one continent to another, I still prefer Lipotype!
Julie Jacquemyn
University of Alberta
Thank you very much for my new and shiny lipidomics data set!
Ilya Levental
University of Virginia
Lipotype Lipidomics is instrumental to our studies of membranes.
Christopher J Stefan
University College London
Lipotype is truly dedicated to supporting scientists in their research.
Anonymous
Anonymous
Contact Lipotype
You are currently viewing a placeholder content from OpenStreetMap. To access the actual content, click the button below. Please note that doing so will share data with third-party providers.
