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Very Long Chain Fatty Acid

We provide MS-based lipid analysis of VLCFA fatty acyls in a variety of sample types and deliver results in six or less weeks.


Fatty Acyls
Lipid Category
Fatty Acids
Lipid Group

About the structure and biological function of VLCFA

Structure. Very long chain fatty acids (VLCFA) belong to the group of fatty acids within the fatty acyls. Their structure consists of a hydrocarbon chain of twenty-two to thirty carbon atoms and a carboxylic head group. The hydrocarbon chain of VLCFAs can further contain multiple double bonds, and be branched or linear.

Function. Very long chain fatty acids occur in many plant waxes and some animal waxes. VLCFAs are predominantly found in the ceramide backbone of sphingolipids. They alter the membrane thickness and rigidity locally and contribute to the formation of lipid rafts, subdomains of the cell membrane. Both, excess and deficiency of VLCFAs in the brain has been linked to neurological disorders. VLCFA level in plasma is used to diagnose adrenoleukodystrophy.

VLCFA lipidomics analysis with

Structural detailsmolecular species
Variants identified > 10
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Delivery time6 weeks
Lipidomics datapmol & mol%


An example for the molecular structure of FA 24:1;0.


Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

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    Friedrich Miescher Institute
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