Home   Lipotype Lipidomics   Phospholipids   Ether Phospholipids 

Ether Phospholipids

We provide MS-based lipid analysis of ether phospholipids in a variety of sample types and deliver results in as little as two weeks.


Lipid Category

About the structure and biological function of Ether Phospholipids

Structure. Ether phospholipids belong to the phospholipids. Their structure consists of a glycerol backbone linked to a phosphorylated “head” group, such as phosphorylcholine or phosphorylethanolamine. Ether phospholipids contain one to two further substituents: at minimum one is a fatty alcohol but no more than one is a fatty acid. Yet, at least one of the two substituents is ether-linked to the glycerol backbone.

Function. Ether phospholipids are found in animals, archaea, and some bacteria but rarely in plants and fungi. They are important structural components of cell membranes and influence their biophysical properties, such as membrane thickness, compression, and rigidness. Ether phospholipids further serve as a store of polyunsaturated fatty acids with important biological functions such as arachidonic acid.

Ether-linked phosphatidylcholine (PC O-), also called platelet activating factor, is the most prominent type of ether phospholipids and induces the aggregation of blood platelets. Ether-linked phosphatidylethanolamine (PE O-) serves as a major biosynthetic precursor of some endocannabinoids, biomolecules serving important neurological functions. Little is known about ether phospholipids with only one substituent.

Ether Phospholipids lipidomics analysis with Lipotype

Covered classes 4
Approach untargeted
Method mass spectrometry
Device Q Exactive Orbitrap (280.000 Res)
Quantification yes
Delivery time 2-6 weeks
Lipidomics data pmol & mol%


Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

  • Thank you once again. The timing is extremely helpful to us.

    Susan Macdonald

    Aldeyra Therapeutics
  • Thank you very much. The results look fantastic!

    Stan Neufeld

    Friedrich Miescher Institute
  • The high-speed turn around when under revision really helped us!

    Rose E Goodchild

    KU Leuven
  • We highly appreciate the personal support and consultation.

    Rainer Voegeli

    DSM Skin Biology
  • We have been quite impressed. The results clearly indicate a difference.

    Pietro De Camilli

    Yale University
  • Cooperating with Lipotype, I enjoy custom packages and great support!

    Olga Ramich

  • After moving from one continent to another, I still prefer Lipotype!

    Julie Jacquemyn

    University of Alberta
  • Thank you very much for my new and shiny lipidomics data set!

    Ilya Levental

    University of Virginia
  • Lipotype Lipidomics is instrumental to our studies of membranes.

    Christopher J Stefan

    University College London
  • Lipotype is truly dedicated to supporting scientists in their research.



Contact Lipotype