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Phosphatidylcholine
We provide MS-based lipid analysis of PC phospholipids in a variety of sample types and deliver results in as little as two weeks.
About the structure and biological function of PC
Structure. Phosphatidylcholines (lecithins, PtdCho, GPCho, or PC) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a phosphocholine molecule. The fatty acids can be of variable length, hydroxylated, and contain double bonds.
Function. Phosphatidylcholines serve as key building blocks for biological membranes, and they play an important role in plasma lipoproteins, the biochemical structures to transport lipids in blood plasma. Phosphatidylcholine is a precursor of acetylcholine, a neurotransmitter. Platelet-activating factor is a phosphatidylcholine. Phosphatidylcholines are elevated in cancers because of the increased demand for membrane constituents, and linked to liver conditions such as non-alcoholic fatty liver disease.
PC lipidomics analysis with
Structural details subspecies level Variants identified > 500 Approach untargeted Method mass spectrometry Device Q Exactive Orbitrap (280.000 Res) Quantification yes Delivery time 2-6 weeks Lipidomics data pmol & mol% Figures included
1 Cells Basic includes:2 Blood Basic includes:
EXAMPLE STRUCTUREPC
EXAMPLEPC 12:0;0_16:1;0
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