Phosphatidyl­choline

We provide MS-based lipid analysis of PC phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of PC

Structure. Phosphatidylcholines (lecithins, PtdCho, GPCho, or PC) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a phosphocholine molecule. The fatty acids can be of variable length, hydroxylated, and contain double bonds.

Function. Phosphatidylcholines serve as key building blocks for biological membranes, and they play an important role in plasma lipoproteins, the biochemical structures to transport lipids in blood plasma.  Phosphatidylcholine is a precursor of acetylcholine,  a neurotransmitter. Platelet-activating factor is a phosphatidylcholine. Phosphatidylcholines are elevated in cancers because of the increased demand for membrane constituents, and linked to liver conditions such as non-alcoholic fatty liver disease.

PC lipidomics analysis with
Lipotype

Structural detailssubspecies level
Variants identified > 500
Approachuntargeted
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Basic includes:
SM, PG, PI, PS, PA, TAG, DAG, PC, PE, CE

2Blood Basic includes:
SM, Cer, PI, LPC, TAG, DAG, PC, LPE, PE, PC O-, PE O-, Chol, CE

EXAMPLE STRUCTURE
PC

An example for the molecular structure of phosphatidylcholine, specifically PC 18:0;0_22:5;0.

EXAMPLE
PC 12:0;0_16:1;0

An example for the molecular structure of phosphatidylcholine, specifically PC 12:0;0_16:1;0.

ABOUT LIPOTYPE

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Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

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