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Ubiquinone/Ubiquinol

We provide MS-based lipid analysis of UQ prenol lipids in a variety of sample types and deliver results in six or less weeks.

Details

Prenol Lipids
Lipid Category
Quinones
Lipid Group

About the structure and biological function of UQ

Structure. Ubiquinones/ubiquinols (coenzyme Q, mitoquinones, CoQ, or UQ) belong to the group of quinones within the prenol lipids category. Their structure consists of a single- or double-ring structure linked to a chain made of five-carbon isoprene units, the building blocks of prenol lipids. Both, the ring structure and the isoprene chain may encompass oxygen containing substituents, the ring structure may further contain hydrocarbon substituents. The primary difference between ubiquinone and ubiquinol is the redox state – ubiquinone is the oxidized form and ubiquinol is the reduced form.

Function. Ubiquinones/ubiquinols are found in all living organisms. Their most prominent and essential biological function is to act as electron carriers between membrane-bound proteins within the electron transport chain to synthesize ATP, the energy-carrying molecule. In plants, ubiquinones/ubiquinols that are providing an electronic connection system for the generation of ATP through photosynthesis are called plastoquinones. Further, UQ possess antioxidant properties protecting membrane proteins and DNA against oxidative damage.

UQ lipidomics analysis with
Lipotype

Structural detailsmolecular species
Variants identified < 10
Approachtargeted
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Quantificationyes
Delivery time6 weeks
Lipidomics datapmol & mol%
Figuresincluded

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