About the structure and biological function of WE
Structure. Wax esters (WE) belong to the group of fatty esters within the fatty acyls. Their structure is based on a long-chain fatty acid. The carboxyl group of the WE fatty acid is linked to a long-chain fatty alcohol. Both, the fatty acid and the fatty alcohol of WE can be of variable length, and may further encompass multiple double bonds, acyl groups, and oxygen containing substituents such as hydroxy and keto groups.
Function. Wax esters are found in the surface coating of plant leaves, insects, or animal skin where they often have multiple biological functions such as limiting water diffusion or protecting from environmental stress. In mammals, WE are mostly produced by sebaceous glands of the skin but also meibomian glands, which produce the protective fluid that covers the eyes. WE appear to serve a variety of purposes from energy storage to buoyancy in marine animals, and both, beeswax and wool wax contain high proportions of wax esters. Further, many species of bacteria are known to produce WE for storage.
WE lipidomics analysis with
|Agilent 1290 HPLC + 6495 Triplequad
|pmol & mol%
Fatty Acids Fatty Esters Fatty Amides Octadecanoids Eicosanoids Docosanoids Glycerol Esters Ester Phospholipids Ether Phospholipids Diphosphatidylglycerols CDP-Glycerols Sphingoid Bases Ceramide Lipids Cerebrosides Diglycosylceramides Phosphosphingolipids Gangliosides Globosides Sulfoglycosphingolipids Cholesterol Lipids Ergosterol Lipids Isoprenoids Quinones
FFA LiFA SCFA MCFA LCFA SFA UFA WE CAR NAE oxiOME oxiODE Pgd LT TX LX IsoP oxiETrE oxiETE oxiEPE MaR RvD PD oxiDPA oxiDHA TAG DAG MAG PA PC PE PG PI PS LPA LPC LPE LPG LPI LPS BMP PC O- PE O- LPC O- LPE O- CL CDP-DAG Sph dhSph SphP dhSphP GlcSph GalSph Cer CerP dhCer doxCer EOdS EOS EOP EOH NdS NS NP NH AdS AS AP AH HexCer GlcCer GalCer DiHexCer LacCer SM CerPE IPC MIPC M(IP)2C GM1 GM2 GM3 GM4 GD1 GD2 GD3 GT1 GT2 GT3 GQ1 Gb3 Gb4 Sulf Chol CE Erg EE Sqe oxiSqe UQ
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