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Phosphatidylinositol
We provide MS-based lipid analysis of PI phospholipids in a variety of sample types and deliver results in as little as two weeks.
About the structure and biological function of PI
Structure. Phosphatidylinositols (PtdIns, GPIns, or PI) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a phosphoinositol molecule. The fatty acids can be of variable length, hydroxylated, and contain double bonds.
Function. Phosphatidylinositols are key membrane components and vital to many cellular processes. They are the major source for arachidonic acid for the synthesis of eicosanoids, bioactive lipids with signaling functions in allergy, inflammation, childbirth, pain perception, cell growth, blood pressure, and more. Further, phosphatidylinositols are the precursors to phosphoinositides with further signaling and other functional activities
PI lipidomics analysis with
Structural details subspecies level Variants identified > 500 Approach untargeted Method mass spectrometry Device Q Exactive Orbitrap (280.000 Res) Quantification yes Delivery time 2-6 weeks Lipidomics data pmol & mol% Figures included
1 Cells Basic includes:2 Blood Basic includes:
EXAMPLE STRUCTUREPI
EXAMPLEPI 18:0;0_22:6;0
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