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Ether-linked Lyso-phosphatidyl­ethanolamine

We provide MS-based lipid analysis of LPE O- phospholipids in a variety of sample types and deliver results in as little as two weeks.
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Details

Phospholipids
Lipid Category
Ether Phospholipids
Lipid Group
Ether-linked Lyso-phosphatidyl­ethanolamine
Lipid Class

About the structure and biological function of LPE O-

Structure. Ether-linked lyso-phosphatidyl-ethanolamines (LPE O-) belong to the group of ether phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty alcohol via an ether bond and a phosphoethanolamine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Little is known about the biological function of ether-linked lyso-phosphatidyl-ethanolamines, but they are precursors to ether-linked phosphatidyl-ethanolamines. In the pigmented layer of the human retina that nourishes retinal visual cells, LPE O- lipids are linked to the formation of bisretinoids. Bisretinoids are a family of fluorescent molecules that form in photoreceptor cells and contribute to some retinal diseases, thus LPE O- lipids are suggested to play a role in retinal health.

See all research articles

LPE O- lipidomics analysis with
Lipotype

Structural detailsspecies level
Variants identified > 25
Approachuntargeted
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Extended includes:
LPA, LPC, LPE, LPG, LPI, LPS, PC O-, PE O-, LPC O-, LPE O-, CL, Cer, HexCer

2Blood Extended includes:
PA, PG, LPA, LPI, LPC O-, LPE O-, HexCer

EXAMPLE STRUCTURE
LPE O-

An example for the molecular structure of ether-linked lyso-phosphatidylethanolamine, specifically LPE O- 18:1;0.

EXAMPLE
LPE O- 18:1;0

An example for the molecular structure of ether-linked lyso-phosphatidylethanolamine, specifically LPE O- 18:1;0.

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LPE O-
analysis?

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Lipid Navigator

Categories

Fatty Acyls Glycerolipids Phospholipids Sphingolipids Sterol Lipids Prenol Lipids

Groups

Fatty Acids Fatty Esters Fatty Amides Octadecanoids Eicosanoids Docosanoids Glycerol Esters Ester Phospholipids Ether Phospholipids Diphospha­tidyl­glycerols CDP-Glycerols Sphingoid Bases Ceramide Lipids Cerebrosides Diglycosyl­ceramides Phospho­sphingolipids Gangliosides Globosides Sulfoglyco­sphingolipids Cholesterol Lipids Ergosterol Lipids Isoprenoids Quinones

Classes

FFA LiFA SCFA MCFA LCFA SFA UFA WE CAR NAE oxiOME oxiODE Pgd LT TX LX IsoP oxiETrE oxiETE oxiEPE MaR RvD PD oxiDPA oxiDHA TAG DAG MAG PA PC PE PG PI PS LPA LPC LPE LPG LPI LPS BMP PC O- PE O- LPC O- LPE O- CL CDP-DAG Sph dhSph SphP dhSphP GlcSph GalSph Cer CerP dhCer doxCer EOdS EOS EOP EOH NdS NS NP NH AdS AS AP AH HexCer GlcCer GalCer DiHexCer LacCer SM CerPE IPC MIPC M(IP)2C GM1 GM2 GM3 GM4 GD1 GD2 GD3 GT1 GT2 GT3 GQ1 Gb3 Gb4 Sulf Chol CE Erg EE Sqe oxiSqe UQ

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