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Diacylglycerol
We provide MS-based lipid analysis of DAG glycerolipids in a variety of sample types and deliver results in as little as two weeks.
About the structure and biological function of DAG
Structure. Diacylglycerols (diglycerides, DAG, or DG) belong to the group of glycerol esters within the glycerolipids. Their structure consists of a glycerol backbone linked to two fatty acids. The fatty acids can be of variable length, hydroxylated, and contain double bonds.
Function. Diacylglycerols have different biological functions, of which many depend on the position of the two fatty acids at the glycerol backbone. Thus, diacylglycerols serve as key intermediates in the synthesis of phospholipids and glycerolipids such as triacylglycerols. They can also function in cellular signaling, and their physical properties influence cell membrane biophysics. They are important immunomodulators. Further, diacylglycerols accumulate in many organs in obesity and can be an important factor in cancer.
DAG lipidomics analysis with Lipotype
Structural details subspecies level Variants identified > 500
Approach untargeted Method mass spectrometry Device Q Exactive Orbitrap (280.000 Res) Quantification yes Delivery time 2-6 weeks Lipidomics data pmol & mol% Figures included
1 Cells Basic includes: SM, PA, PC, PE, PG, PI, PS, TAG, DAG, CE2 Blood Basic includes: SM, Cer, PC, PE, PI, TAG, DAG, LPC, LPE, PC O-, PE O-, Chol, CE3 Skin includes: TAG, DAG, Chol, CE
EXAMPLE STRUCTUREDAG
EXAMPLEDAG 18:0;0_20:5;0
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