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We provide MS-based lipid analysis of TX fatty acyls in a variety of sample types and deliver results in eight or less weeks.


Fatty Acyls
Lipid Category
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About the structure and biological function of TX

Structure. Thromboxanes (TX) belong to the group of eicosanoids within the fatty acyls. Their structure is based on eicosanoic acid, a twenty carbon atoms long hydrocarbon chain with a carboxyl group. The chain contains one six-membered ether-containing ring made of the carbon atoms eight to twelve. All thromboxanes contain at least a hydroxyl group on carbon atom 15 and a double bond at carbon atom 13.

Function. Thromboxanes exert hormone-like functions. They interact with G-protein-linked receptors on the cell surface to activate signal transduction pathways inside the cell. TXs modify inflammatory responses but are most well-known for their role in platelet aggregation, vasoconstriction, and smooth muscle proliferation – they are an essential part of the wound repair mechanism. Thromboxane synthesis and thus platelet aggregation is inhibited by non-steroidal anti-inflammatory drugs like aspirin.

TX lipidomics analysis with

Structural detailsmolecular species
Variants identified < 10
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Delivery time6 weeks
Lipidomics datapmol & mol%
Figuresin development


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