About the structure and biological function of NAE
Structure. Endocannabinoids (NAE) belong to the group of fatty amides within the fatty acyls. Their structure is based on a fatty acid which is often eicosanoic acid, a twenty carbon atoms long hydrocarbon chain with a carboxyl group. The carboxyl group of endocannabinoids is linked to an ethanolamine molecule. The hydrocarbon chain of NAEs may further encompass multiple double bonds and oxygen containing substituents such as hydroxy and epoxy groups.
Function. Endocannabinoids all produce similar biological results through activating the G-protein-linked receptors CB1 and CB2. They act as signaling molecules and their biological function mainly relates to modifying metabolic and physiological processes. The specific effect of an endocannabinoid is subject to the interaction of CB1 and CB2 with further G proteins which in turn is dependent on factors, such as cell type and subcellular location. Thus, NAEs impact a wide variety of cellular processes.
Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.
★★★★★
Thank you once again. The timing is extremely helpful to us.
Susan Macdonald
Aldeyra Therapeutics
Thank you very much. The results look fantastic!
Stan Neufeld
Friedrich Miescher Institute
The high-speed turn around when under revision really helped us!
Rose E Goodchild
KU Leuven
We highly appreciate the personal support and consultation.
Rainer Voegeli
DSM Skin Biology
We have been quite impressed. The results clearly indicate a difference.
Pietro De Camilli
Yale University
Cooperating with Lipotype, I enjoy custom packages and great support!
Olga Ramich
DIfE
After moving from one continent to another, I still prefer Lipotype!
Julie Jacquemyn
University of Alberta
Thank you very much for my new and shiny lipidomics data set!
Ilya Levental
University of Virginia
Lipotype Lipidomics is instrumental to our studies of membranes.
Christopher J Stefan
University College London
Lipotype is truly dedicated to supporting scientists in their research.
Anonymous
Anonymous
Contact Lipotype
You are currently viewing a placeholder content from OpenStreetMap. To access the actual content, click the button below. Please note that doing so will share data with third-party providers.