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Phospholipids

We provide MS-based lipid analysis of phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of Phospholipids

Structure. Phospholipids are one of the eight categories of lipids and encompass tens of thousands of lipid species. All of these feature a similar molecular structure: they consist of a glycerol backbone linked to a phosphorylated “head” group. Phospholipids further contain one to two ester- or ether-linked fatty acids or fatty alcohols.

Function. Phospholipids are found in the biological membranes of cells of all living organisms. But depending on the specific organism, the types of discoverable phospholipids can greatly vary. Ester phospholipids belong to the most investigated phospholipids, and feature innumerous biological functions. They are the major component of all biological membranes and regulate many cellular functions.

Ether phospholipids influence biophysical properties of biological membranes, and some serve further functions such as platelet aggregation. CDP-glycerols occupy a biosynthetic branch point in phospholipids but also glycerolipids. Diphosphatidylglycerols, a unique type of phospholipids, are structural components of membranes related to the generation of cellular energy.

Phospholipids lipidomics analysis with Lipotype

Covered classes 19
Approach untargeted/targeted
Method mass spectrometry
Device Q Exactive Orbitrap (280.000 Res)
or
Agilent 1290 HPLC + 6495 Triplequad
Quantification yes
Delivery time 2-6 weeks
Lipidomics data pmol & mol%

ABOUT LIPOTYPE

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

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    Friedrich Miescher Institute
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    KU Leuven
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    University of Alberta
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    University of Virginia
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    University College London
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