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Lyso-phosphatidyl­ethanolamine

We provide MS-based lipid analysis of LPE phospholipids in a variety of sample types and deliver results in as little as two weeks.
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Details

Phospholipids
Lipid Category
Ester Phospholipids
Lipid Group
Lyso-phosphatidyl­ethanolamine
Lipid Class

About the structure and biological function of LPE

Structure. Lyso-phosphatidyl-ethanolamines (lysocephalins, LysoPtdEtn, LysoPE, or LPE) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphoethanolamine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Lyso-phosphatidyl-ethanolamines are involved in cellular processes such as differentiation and migration of certain neuronal cells, but also of various cancer cells. In plants, LPEs function as inhibitors for a key enzyme in membrane lipid degradation, thus retarding senescence of leaves, flowers, and fruits. They are used commercially to stimulate ripening and extend shelf-life of fruit, and increase vase life of cut flowers. Further, LPE lipids serve as precursors for phosphatidyl-ethanolamines.

Research articles

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LPE lipidomics analysis with
Lipotype

Structural detailsspecies level
Variants identified > 50
Approachuntargeted
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Extended includes:
LPA, LPC, LPE, LPG, LPI, LPS, PC O-, PE O-, LPC O-, LPE O-, CL, Cer, HexCer

2Blood Basic includes:
TAG, DAG, PC, PE, PI, LPC, LPE, PC O-, PE O-, Cer, SM, Chol, CE

EXAMPLE STRUCTURE
LPE

An example for the molecular structure of lyso-phosphatidylethanolamine, specifically LPE 22:5;0.

EXAMPLE
LPE 18:0;0

An example for the molecular structure of lyso-phosphatidylethanolamine, specifically LPE 18:0;0.

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Categories

Fatty Acyls Glycerolipids Phospholipids Sphingolipids Sterol Lipids Prenol Lipids

Groups

Fatty Acids Fatty Aldehydes Fatty Esters Fatty Amides Heptadecanoids Octadecanoids Eicosanoids Docosanoids Glycerol Esters Ester Phospholipids Ether Phospholipids Diphospha­tidyl­glycerols CDP-Glycerols Sphingoid Bases Ceramide Lipids Cerebrosides Diglycosyl­ceramides Phospho­sphingolipids Gangliosides Globosides Sulfoglyco­sphingolipids Cholesterol Lipids Ergosterol Lipids Isoprenoids Quinones

Classes

FFA BCFA SCFA MCFA LCFA VLCFA oxiFAL WE CAR NAE oxiHTrE oxiOME oxiODE oxiOTrE Pgd LT TX LX IsoP RvE oxiEDE oxiETrE oxiETE oxiEPE MaR RvD PD oxiDPA oxiDHA TAG DAG MAG PA PC PE PG PI PS LPA LPC LPE LPG LPI LPS BMP PC O- PE O- LPC O- LPE O- CL CDP-DAG Sph dhSph SphP dhSphP GlcSph GalSph Cer CerP dhCer doxCer EOdS EOS EOP EOH NdS NS NP NH AdS AS AP AH HexCer GlcCer GalCer DiHexCer LacCer SM CerPE IPC MIPC M(IP)2C GM1 GM2 GM3 GM4 GD1 GD2 GD3 GT1 GT2 GT3 GQ1 Gb3 Gb4 Sulf Chol CE oxiChol Lano Desm Lath Erg EE C10T C15T Sqe oxiSqe UQ
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