Lyso-phosphatidyl­ethanolamine

We provide MS-based lipid analysis of LPE phospholipids in a variety of sample types and deliver results in as little as two weeks.

About the structure and biological function of LPE

Structure. Lyso-phosphatidyl-ethanolamines (lysocephalins, LysoPtdEtn, LysoPE, or LPE) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphoethanolamine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Lyso-phosphatidyl-ethanolamines are involved in cellular processes such as differentiation and migration of certain neuronal cells, but also of various cancer cells. In plants, LPEs function as inhibitors for a key enzyme in membrane lipid degradation, thus retarding senescence of leaves, flowers, and fruits. They are used commercially to stimulate ripening and extend shelf-life of fruit, and increase vase life of cut flowers. Further, LPE lipids serve as precursors for phosphatidyl-ethanolamines.

LPE lipidomics analysis with
Lipotype

Structural detailsspecies level
Variants identified > 50
Approachuntargeted
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Extended includes:
Cer, LPA, LPC, HexCer, LPE, LPG, LPI, LPS, PC O-, PE O-, LPC O-, LPE O-, CL

2Blood Basic includes:
SM, Cer, PI, LPC, TAG, DAG, PC, LPE, PE, PC O-, PE O-, Chol, CE

EXAMPLE STRUCTURE
LPE

An example for the molecular structure of lyso-phosphatidylethanolamine, specifically LPE 22:5;0.

EXAMPLE
LPE 18:0;0

An example for the molecular structure of lyso-phosphatidylethanolamine, specifically LPE 18:0;0.

ABOUT LIPOTYPE

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