Oxidized Docosa­pentaenoic Acid

We provide MS-based lipid analysis of oxiDPA fatty acyls in a variety of sample types and deliver results in eight or less weeks.

Details

Fatty Acyls
Lipid Category
Docosanoids
Lipid Group

About the structure and biological function of oxiDPA

Structure. Oxidized docosapentaenoic acids (oxiDPA) belong to the group of docosanoids within the fatty acyls. Their structure is based on docosanoic acid, a twenty-two carbon atoms long hydrocarbon chain with a carboxyl group. The chain contains five double bonds, from which their name derives. OxiDPAs may further encompass multiple hydroxy groups as well as other oxygen containing substituents.

Function. Oxidized docosapentaenoic acids are important to neurodevelopment and neuroprotection, as well as cardiovascular disease prevention. OxiDPAs are biosynthetic intermediates to a variety of other docosanoid lipids. Further, oxiDPA lipids may be linked to some of the beneficial effects of dietary omega-3 fatty acids.

oxiDPA lipidomics analysis with
Lipotype

Structural detailsmolecular species
Variants identified > 10
Approachtargeted
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Quantificationyes
Delivery time8 weeks
Lipidomics datapmol & mol%
Figuresin development

EXAMPLE STRUCTURE
oxiDPA

An example for the molecular structure of 19,20-DiHDPE.

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