Oxidized Docosa­pentaenoic Acid

We provide MS-based lipid analysis of oxiDPA fatty acyls in a variety of sample types and deliver results in six or less weeks.

Details

Fatty Acyls
Lipid Category
Docosanoids
Lipid Group

About the structure and biological function of oxiDPA

Structure. Oxidized docosapentaenoic acids (oxiDPA) belong to the group of docosanoids within the fatty acyls. Their structure is based on docosanoic acid, a twenty-two carbon atoms long hydrocarbon chain with a carboxyl group. The chain contains five double bonds, from which their name derives. OxiDPAs may further encompass multiple hydroxy groups as well as other oxygen containing substituents.

Function. Oxidized docosapentaenoic acids are important to neurodevelopment and neuroprotection, as well as cardiovascular disease prevention. OxiDPAs are biosynthetic intermediates to a variety of other docosanoid lipids. Further, oxiDPA lipids may be linked to some of the beneficial effects of dietary omega-3 fatty acids.

Oxidized Docosa­pentaenoic Acid lipidomics analysis with Lipotype

Structural details molecular species
Variants identified > 10
Approach targeted
Method mass spectrometry
Device Agilent 1290 HPLC + 6495 Triplequad
Quantification yes
Delivery time 6 weeks
Lipidomics data pmol & mol%
Figuresyes

Example Structure
oxiDPA

An example for the molecular structure of 19,20-DiHDPE.

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