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Phosphatidylglycerol
We provide MS-based lipid analysis of PG phospholipids in a variety of sample types and deliver results in as little as two weeks.
About the structure and biological function of PG
Structure. Phosphatidylglycerols (PtdGro, GPGro, or PG) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a phosphoglycerol molecule. The fatty acids can be of variable length, hydroxylated, and contain double bonds.
Function. Phosphatidylglycerols are key intermediates in the biosynthesis of many lipids but especially of cardiolipin. They are essential for the development of normal membranes of chloroplasts and mitochondria in higher plants. In bacteria, phosphatidylglycerols are important for optimal functioning of the bacterial machinery and play a role in protein folding and binding. Further, phosphatidylglycerols have a role in the regulation of the innate immune response in the lungs.
PG lipidomics analysis with
Structural details subspecies level Variants identified > 500 Approach untargeted Method mass spectrometry Device Q Exactive Orbitrap (280.000 Res) Quantification yes Delivery time 2-6 weeks Lipidomics data pmol & mol% Figures included
1 Cells Basic includes:2 Blood Extended includes:
EXAMPLE STRUCTUREPG
EXAMPLEPG 14:1;0_16:0;0
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