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We provide MS-based lipid analysis of Sqe prenol lipids in a variety of sample types and deliver results in six or less weeks.


Prenol Lipids
Lipid Category
Lipid Group
Lipid Class

About the structure and biological function of Sqe

Structure. Squalene (Sqe) belongs to the group of isoprenoids within the prenol lipids category. Their structure is based on a linear chain of six five-carbon isoprene units, the building blocks of prenol lipids. Squalene does not encompass further hydrocarbon or oxygen containing substituents.

Function. Squalene serves an important biological function as key precursor to sterol lipids and hopanoids. In most tissues of eukaryotes, squalene is a minor component. Yet Sqe accumulates in sebum, a complex mixture of lipids secreted by the sebaceous glands of mammal skin where it is thought to provide softening effects in the epidermis. Sqe can also break lipid peroxidation by quenching free radicals. Further, squalene is an important component of the vaccine adjuvants AS03 and MF59 which are co-administered with vaccines to stimulate the immune system and increase vaccine efficiency.

Sqe lipidomics analysis with

Structural detailsclass level
Variants identified 1
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Delivery time6 weeks
Lipidomics datapmol & mol%
Figuresin development


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