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Cholesterol

We provide MS-based lipid analysis of Cholesterol in a variety of sample types and deliver results in as little as two weeks.

Details

Sterol Lipids
Lipid Category
Cholesterol
Lipid Class

About the structure and biological function of Chol

Structure. Cholesterol (Chol) belongs to the group of cholesterol lipids within the sterol lipids. Its structure consists of four linked hydrocarbon rings, the steroid structure. A hydrocarbon tail is linked to one end of the steroid, a hydroxyl group linked to the other end.

Function. Cholesterol has a vital function in animals. It is an essential component of cell membranes and lipid rafts. It is a precursor of steroid hormones and other metabolites such as vitamin D or bile acids. Cholesterol also is important for cell signaling, transport processes, and regulation of gene readout, and an abundant constituent of the water permeability barrier in skin and of myelin in the brain. Further, excess cholesterol is linked to cardiovascular disease.

Chol lipidomics analysis with
Lipotype

Structural detailsclass level
Variants identified 1
Approachuntargeted
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Blood Basic includes:
TAG, DAG, PC, PE, PI, LPC, LPE, PC O-, PE O-, Cer, SM, Chol, CE

2Skin includes:
TAG, DAG, EOdS, EOS, EOP, EOH, NdS, NS, NP, NH, AdS, AS, AP, AH, Chol, CE


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