Cholesterol

We provide MS-based lipid analysis of Cholesterol in a variety of sample types and deliver results in as little as two weeks.

Details

Sterol Lipids
Lipid Category
Cholesterol
Lipid Class

About the structure and biological function of Chol

Structure. Cholesterol (Chol) belongs to the group of cholesterol lipids within the sterol lipids. Its structure consists of four linked hydrocarbon rings, the steroid structure. A hydrocarbon tail is linked to one end of the steroid, a hydroxyl group linked to the other end.

Function. Cholesterol has a vital function in animals. It is an essential component of cell membranes and lipid rafts. It is a precursor of steroid hormones and other metabolites such as vitamin D or bile acids. Cholesterol also is important for cell signaling, transport processes, and regulation of gene readout, and an abundant constituent of the water permeability barrier in skin and of myelin in the brain. Further, excess cholesterol is linked to cardiovascular disease.

Cholesterol lipidomics analysis with Lipotype

Structural details class level
Variants identified 1
Approach untargeted/targeted
Method mass spectrometry
Device Q Exactive Orbitrap (280.000 Res)
or
Agilent 1290 HPLC + 6495 Triplequad
Quantification yes
Delivery time 2-6 weeks
Lipidomics data pmol & mol%
Figuresyes
1Skin includes:
TAG, DAG, EOdS, EOS, EOP, EOH, NdS, NS, NP, NH, AdS, AS, AP, AH, Chol, CE

2Blood Basic includes:
TAG, DAG, PC, PE, PI, LPC, LPE, PC O-, PE O-, Cer, SM, Chol, CE

Example Structure
Chol

General molecular structure of cholesterol.

Lipid Navigator


ABOUT LIPOTYPE

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

  • Thank you once again. The timing is extremely helpful to us.

    Susan Macdonald

    Aldeyra Therapeutics
  • Thank you very much. The results look fantastic!

    Stan Neufeld

    Friedrich Miescher Institute
  • The high-speed turn around when under revision really helped us!

    Rose E Goodchild

    KU Leuven
  • We highly appreciate the personal support and consultation.

    Rainer Voegeli

    DSM Skin Biology
  • We have been quite impressed. The results clearly indicate a difference.

    Pietro De Camilli

    Yale University
  • Cooperating with Lipotype, I enjoy custom packages and great support!

    Olga Ramich

    DIfE
  • After moving from one continent to another, I still prefer Lipotype!

    Julie Jacquemyn

    University of Alberta
  • Thank you very much for my new and shiny lipidomics data set!

    Ilya Levental

    University of Virginia
  • Lipotype Lipidomics is instrumental to our studies of membranes.

    Christopher J Stefan

    University College London
  • Lipotype is truly dedicated to supporting scientists in their research.

    Anonymous

    Anonymous

Contact Lipotype