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Sphinganine

We provide MS-based lipid analysis of dhSph sphingolipids in a variety of sample types and deliver results in six or less weeks.

Details

Sphingolipids
Lipid Category
Sphingoid Bases
Lipid Group
Sphinganine
Lipid Class

About the structure and biological function of dhSph

Structure. Sphinganines (dihydrosphingosines, D-erythro-sphinganines, or dhSph) belong to the group of sphingoid bases within the sphingolipids. Their structure consists of an amino alcohol with a saturated hydrocarbon chain.

Function. Sphinganines serve an important biological function as biosynthetic precursors to sphingosine and thus more complex sphingolipids. Little is known about the cell biological function of free sphinganines aside their difference from sphingosines. However, it has been linked to sleep apnea and sepsis. Additionally, some fungi produce sphinganine analog mycotoxins to disrupt sphingolipid metabolism in plants.

dhSph lipidomics analysis with
Lipotype

Structural detailsmolecular species
Variants identified < 10
Approachtargeted
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Quantificationyes
Delivery time6 weeks
Lipidomics datapmol & mol%
Figuresincluded

EXAMPLE STRUCTURE
dhSph

An example for the molecular structure of sphinganine, specifically SPB 18:0;O2.

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