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We provide MS-based lipid analysis of doxCer sphingolipids in a variety of sample types and deliver results in six or less weeks.


Lipid Category
Ceramide Lipids
Lipid Group
Lipid Class

About the structure and biological function of doxCer

Structure. Deoxyceramides (deoxyCer, or doxCer) belong to the group of ceramide lipids within the sphingolipids. Their structure consists of a sphingoid base, specifically deoxysphingosine, and a fatty acid. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Deoxyceramides augment the presentation of small glycolipid antigens to T cells and have been linked to therapy-induced senescence, a state of cell cycle arrest in response to chemotherapy. High levels of deoxyCer have also been found in obese patients with type 2 diabetes and dietary interventions have been shown to affect these. Deoxyceramides are suggested to be potential biomarkers insulin sensitivity.

doxCer lipidomics analysis with

Structural detailsmolecular species
Variants identified > 10
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Delivery time6 weeks
Lipidomics datapmol & mol%


An example for the molecular structure of deoxyceramide, specifically deoxyCer(m18:1;1/16:0;0).


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