Prostaglandin
Details
Lipid Category
Lipid Group
Lipid Class
About the structure and biological function of Pgd
Structure. Prostaglandins (Pgd) belong to the group of eicosanoids within the fatty acyls. Their structure consists is based on eicosanoic acid, a twenty carbon atoms long hydrocarbon chain with a carboxyl group. The chain contains one five-membered ring made of the carbon atoms eight to twelve. The substituents of the ring define the name of the Pgd species and all prostaglandins contain at least a hydroxyl group on carbon atom 15 and a double bond at carbon atom 13.
Function. Prostaglandins are associated with hormone-like functions. They interact with G-protein-linked receptors on the cell surface to activate cellular signal transduction pathways. Pgds coordinate a multitude of physiological processes, sometimes opposing depending on cell type and stimuli. The best-known function of Pgds in cells is that they modify inflammatory response. Prostaglandin synthesis is inhibited by non-steroidal anti-inflammatory drugs like aspirin to limit their pro-inflammatory effects.
Pgd lipidomics analysis with
Lipotype
Structural details | molecular species |
Variants identified | > 25 |
Approach | targeted |
Method | mass spectrometry |
Device | Agilent 1290 HPLC + 6495 Triplequad |
Quantification | yes |
Delivery time | 8 weeks |
Lipidomics data | pmol & mol% |
Figures | in development |
EXAMPLE STRUCTURE
Pgd

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Pgd
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