About the structure and biological function of CDP-DAG
Structure. CDP-diacylglycerols (cytidine-diphosphate-diglycerides, CDP-diglycerides, or CDP-DAG) belong to the group of CDP-glycerols within the phospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a cytidine diphosphate molecule (CDP). The fatty acids can be of variable length, hydroxylated, and contain double bonds.
Function. CDP-DAG lipids occupy a branch point in the biosynthesis of complex glycerolipids. The distinct end-products depend on the subcellular location of synthesis. For example, CDP-DAGs are used for cardiolipin biosynthesis in mitochondria and for phosphatidylinositol and phosphatidylglycerol synthesis in the endoplasmic reticulum. Thus, CDP-DAG lipids also have a key role in regulation of phosphatidylinositol signal transduction. Further, they are linked to lipid droplet size in adipocytes.
CDP-DAG lipidomics analysis with
|Structural details||species level|
|Variants identified||< 10|
|Device||Q Exactive Orbitrap (280.000 Res)|
|Delivery time||2-4 weeks|
|Lipidomics data||pmol & mol%|
CDP-DAG, IPC, MIPC, M(IP)2C, Erg, EE
Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.
You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!