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Bis(monoacylglycero)phosphate

We provide MS-based lipid analysis of BMP phospholipids in a variety of sample types and deliver results in six or less weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of BMP

Structure. Bis-(monoacylglycero)-phosphates (LBPA, or BMP) belong to the group of ester phospholipids within the phospholipids. Their structure consists of two monoacylglycerols linked to each other via a phosphate. In total, BMPs contain two ester-linked fatty acids. They can be of variable length, hydroxylated, and contain double bonds.

Function. Bis-(monoacylglycero)-phosphates play diverse roles in cellular physiology and disease. They are markedly enriched in endosomal and lysosomal vesicles and are involved in membrane docking and digestion, and play a role in lysosomal storage diseases. BMPs are also researched as a non-invasive biomarker to monitor phospholipidosis with drug-induced toxicities. Further, BMPs have been identified as an important actor in the host endocytic machinery hijacked by certain viruses.

BMP lipidomics analysis with
Lipotype

Structural detailsmolecular species
Variants identified > 10
Approachtargeted
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Quantificationyes
Delivery time6 weeks
Lipidomics datapmol & mol%
Figuresincluded

ABOUT LIPOTYPE

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

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    Friedrich Miescher Institute
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