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Phosphatidylserine
We provide MS-based lipid analysis of PS phospholipids in a variety of sample types and deliver results in as little as two weeks.
About the structure and biological function of PS
Structure. Phosphatidyl-serines (PtdSer, GPSer, or PS) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a phosphoserine molecule. The fatty acids can be of variable length, hydroxylated, and contain double bonds.
Function. Phosphatidyl-serines are essential membrane components and contribute to the organization of protein complexes on the cytosolic side of the membrane, thus facilitating signaling activities. They also serve as precursors for lyso-phosphatidylserines, and for phosphatidylethanolamines. They are essential cofactors that bind to and activate many proteins with signaling functions. Further, phosphatidylserines are an important element of the blood coagulation process in platelets, and have a role in regulation of apoptosis, programmed cell death.
PS lipidomics analysis with
Structural details subspecies level Variants identified > 500 Approach untargeted Method mass spectrometry Device Q Exactive Orbitrap (280.000 Res) Quantification yes Delivery time 2-6 weeks Lipidomics data pmol & mol% Figures included
1 Cells Basic includes:
EXAMPLE STRUCTUREPS
EXAMPLEPS 16:1;0_26:0;0
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