Cholesterol Lipids

We provide MS-based lipid analysis of cholesterol lipids in a variety of sample types and deliver results in as little as two weeks.

Details

Sterol Lipids
Lipid Category

About the structure and biological function of Cholesterol Lipids

Structure. Cholesterol lipids belong to the sterol lipids. Their structure consists of the steroid structure, four linked hydrocarbon rings, to which a characteristic carbon side-chain is attached and two further methyl groups. The steroid structure, the side-chains, and the methyl groups can be modified – hundreds of cholesterol lipids have been discovered.

Function. Cholesterol lipids belong to the sterol lipids. Their structure consists of the steroid structure, four linked hydrocarbon rings, to which a characteristic carbon side-chain is attached and two further methyl groups. The steroid structure, the side-chains, and the methyl groups can be modified – hundreds of cholesterol lipids have been discovered.

Cholesteryl esters (CE) are cholesterol lipids with a fatty acid ester-linked to the steroid structure. They function as cholesterol transport form but also as cellular pool for both of its components, cholesterol and the fatty acid. Relatively little is known about cholesterol lipids with further modifications but some oxidized cholesterol lipids are linked to lipid metabolism abnormalities.

Cholesterol Lipids lipidomics analysis with Lipotype

Covered classes2
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded

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