Home   Lipotype Lipidomics   Sterol Lipids   Cholesterol Lipids 

Cholesterol Lipids

We provide MS-based lipid analysis of cholesterol lipids in a variety of sample types and deliver results in as little as two weeks.


Sterol Lipids
Lipid Category

About the structure and biological function of Cholesterol Lipids

Structure. Cholesterol lipids belong to the sterol lipids. Their structure consists of the steroid structure, four linked hydrocarbon rings, to which a characteristic carbon side-chain is attached and two further methyl groups. The steroid structure, the side-chains, and the methyl groups can be modified – hundreds of cholesterol lipids have been discovered.

Function. Cholesterol lipids are mostly found in animals. Cholesterol itself is an essential component of plasma membranes where it participates in the formation of lipid rafts. It is a biosynthetic precursor of steroid hormones but also important for cell signaling, transport processes, and regulation of gene readout. Further, excess cholesterol is linked to cardiovascular disease.

Cholesteryl esters (CE) are cholesterol lipids with a fatty acid ester-linked to the steroid structure. They function as cholesterol transport form but also as cellular pool for both of its components, cholesterol and the fatty acid. Relatively little is known about cholesterol lipids with further modifications but some oxidized cholesterols (oxiChol) are linked to lipid metabolism abnormalities.

Cholesterol Lipids lipidomics analysis with Lipotype

Covered classes 6
Approach untargeted/targeted
Method mass spectrometry
Device Q Exactive Orbitrap (280.000 Res)
Agilent 1290 HPLC + 6495 Triplequad
Quantification yes
Delivery time 2-6 weeks
Lipidomics data pmol & mol%


Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

  • Thank you once again. The timing is extremely helpful to us.

    Susan Macdonald

    Aldeyra Therapeutics
  • Thank you very much. The results look fantastic!

    Stan Neufeld

    Friedrich Miescher Institute
  • The high-speed turn around when under revision really helped us!

    Rose E Goodchild

    KU Leuven
  • We highly appreciate the personal support and consultation.

    Rainer Voegeli

    DSM Skin Biology
  • We have been quite impressed. The results clearly indicate a difference.

    Pietro De Camilli

    Yale University
  • Cooperating with Lipotype, I enjoy custom packages and great support!

    Olga Ramich

  • After moving from one continent to another, I still prefer Lipotype!

    Julie Jacquemyn

    University of Alberta
  • Thank you very much for my new and shiny lipidomics data set!

    Ilya Levental

    University of Virginia
  • Lipotype Lipidomics is instrumental to our studies of membranes.

    Christopher J Stefan

    University College London
  • Lipotype is truly dedicated to supporting scientists in their research.



Request Analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!