Lyso-phosphatidylcholine

We provide MS-based lipid analysis of LPC phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of LPC

Structure. Lyso-phosphatidyl-cholines (lysolecithin, LysoPtdCho, LysoPC, or LPC) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphocholine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Lyso-phosphatidyl-cholines are potent signaling molecules and they have many functions related to inflammation and the immune system. They are suggested an important factor for neurodegeneration such as cognitive decline and dementia, and promote demyelination of neurons. Impaired levels of LPCs are also linked to cardiovascular disease and cancers. They have some functions in cell signaling. Further, LPC lipids have beneficial effects by activating macrophages.

LPC lipidomics analysis with
Lipotype

Structural detailsspecies level
Variants identified > 100
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Extended includes:
PC O-, CL, Cer, HexCer, PE O-, LPC O-, LPE O-, LPA, LPC, LPE, LPG, LPI, LPS

2Blood Basic includes:
PC O-, SM, Cer, TAG, DAG, PC, PE O-, PE, PI, LPC, LPE, Chol, CE

STRUCTURE
LPC

General molecular structure of lyso-phosphatidylcholine.

EXAMPLE
LPC 16:0;0

An example for the molecular structure of lyso-phosphatidylcholine, specifically LPC 16:0;0.

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