Tag Lipotype

Lipotype is GMP certified!

Henri Deda April 16, 2019

Good Manufacturing Practices (GMP) ensure safety and quality of pharmaceutical products. Lipotype is the worldwide first and only officially GMP certified shotgun lipidomics service provider for pharmaceutical applications.

The need for GMP regulations
Quality variations can pose direct threats to patient health – especially in the pharma industry. This is why quality control plays a central role in manufacturing and developing pharmaceutical products. GMP certifications are issued by governmental authorities to ensure product quality and compliance with mandatory health agency requirements.

As worldwide first and only shotgun lipidomics service provider with official GMP certificate by state authority, Lipotype now offers untargeted, global and absolutely quantitative lipidomics analysis services according to GMP regulation laid down in Directive 2003/94/EC.

GMP-compliant lipidomics services
Pharma researchers challenging therapeutic limitations by developing new pharmaceutical products can draw on Lipotype Shotgun Lipidomics services beyond lipidomic analysis of content, purity and stability. Development of GMP compliant analytical tests and release analysis of compounds from clinical trials to market release complete the portfolio of GMP certified lipid analysis services.

Resources

Press Release: Worldwide first and only shotgun lipidomics service provider with official GMP certificate

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New method for molecular profiling of adipose tissue

Henri Deda March 13, 2019

The Paul Langerhans Institute Dresden, a partner of the DZD, and the University Hospital Carl Gustav Carus joined their forces with Lipotype GmbH and developed a new shotgun lipidomics method for the molecular profiling of brown and white adipose tissue. The results of this collaborative work have now been published in the journal ́Molecular Metabolism ́.

To better understand adipose tissue
Adipose tissue consists of more than 99% of storage lipids, mainly triglycerides that are stored within the cell in so-called lipid droplets. Nonetheless, the remaining 0.5-1% of lipids are sufficient to build a metabolically active cell in all its complexity.

Despite the enormous importance of adipose tissue in human health and diseases (like diabetes), no standardized method existed so far, to quantitatively and reproducibly analyze its lipidome. Thus, Paul Langerhans Institute Dresden (PLID), German Center for Diabetes Research (DZD), the Institute for Clinical Chemistry and Laboratory Medicine of the University Hospital Carl Gustav Carus Dresden (IKL) and Lipotype GmbH chose to tackle this urgent need. Their joint vision of an omics-driven clinic, fueled the development of a shotgun lipidomics protocol for adipose tissue.

A new protocol
This new and validated protocol wants to facilitate the systematic molecular profiling of adipose tissue by providing high reproducibility and linear dynamic range for all lipid classes. Besides covering all types of adipose tissue, it can be used for fatty organs, and can be integrated with further omics approaches used in pre-clinical research.

Resources

Press Release: Dresden scientists develop new shotgun lipidomics method for molecular profiling of adipose tissue

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Lipidomics: A Rising Star in Omics Research

Henri Deda February 15, 2019

Technology Networks published a new introductory article on lipidomics last week. They spoke to Dr. Christian Klose about applications in the field of lipid research and to Henri Deda about LEA, the new Lipidomics Excellence Award.

The article in short
The article provides a brief introduction to the research field of lipids: lipidomics. Summarizing recent developments and challenges of the past, granting an overview on today’s lipidomics technology and discussing the broad field of lipidomics applications in detail, the article is a short and entertaining read. Dr Christian Klose, Head of Research and Development at Lipotype, comments on various aspects providing examples for current research and product developments in various industries and academia. To complete the picture of current developments in lipidomics, the motivation to found and organize the Lipidomics Excellence Award finishes off the article.

Lipidomics Excellence Award
LEA, the Lipidomics Excellence Award, has been created to promote, support and strengthen researchers who are eager to contribute to the progress of life sciences through lipidomics. Up to three individuals with ongoing research are awarded with comprehensive research prizes to support their projects. Applications are open to all researchers who are eager to strengthen life sciences through lipidomics. Call for applications is open till March 30, 2019.

LEA is supported by LIPID MAPS, SwissLipids and Lipotype; the media LABO, the Journal of Lipid Research and transkript aligned themselves with LEA too.

Resources

Technology Networks Article: Lipidomics – A Rising Star in “OMICS” Research
Press Release: Lipotype Launches first global Lipidomics Excellence Award

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Lipotype launches first global Lipidomics Excellence Award

Henri Deda January 16, 2019

Lipotype announces LEA, the Lipidomics Excellence Award, for breakthrough lipidomics projects. Call for applications is open till March 30, 2019.

LEA at a glance
LEA has been created to promote, support and strengthen researchers who are eager to contribute to the progress of life sciences through lipidomics.

Up to three individuals with ongoing research are awarded with comprehensive research prizes to support their projects. Applications are open to all researchers who are eager to strengthen life sciences through lipidomics.

The awardees are selected by a panel composed of internationally renown members of academia, each of them recognized as leading experts in their respective fields.

LEA is supported by LIPID MAPS, SwissLipids and Lipotype.

The first prize
The winner of the first prize will receive 55,000 EUR worth of analysis services in order to put their idea to test. The awardee will be presenting their research at an internationally leading experts summit for lipids and lipidomics, the EMBO Workshop “Lipid function in health and disease” in Dresden (Sept 27th – 30th, 2019). A press conference will be held to present the project and formally handover the LEA 2019 trophy.

How to apply
Individual researchers from academia and industry and their ongoing projects can apply for LEA 2019. Applicants are asked to outline their idea for a project or research approach whose results they think can be boosted by a detailed lipid analysis. All applications shall be submitted until March 30, 2019 via the online submission form.

Resources

Press Release: Lipotype Launches first global Lipidomics Excellence Award – ENG
Press Release: Lipotype startet den ersten weltweiten Lipidomics Excellence Award – DEU
Online Submission Form

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Lipotype presents the awardees of the Lipidomics Forum 2018

Henri Deda November 19, 2018

We proudly present the winners of best poster and best scientific talk award at the Lipidomics Forum 2018.

A short history of the Lipidomics Forum
The Lipidomics Forum is a joint effort of the ISAS Dortmund and the Research Center Borstel. The annual symposium is a series of conferences on lipid biology and lipidomics to provide a platform for international acknowledged scientists, students, and young researchers to interact. It does not only cover current research highlights but also offers tutorials on selected methodical topics.

The Lipidomics Forum has become a home for Lipotype. Besides a shared scientific background, we strive for the same goals such as global scientific excellence and exchange. This is why Lipotype began attending and supporting through awards the conference many years ago.

The awardees
The best poster award was won by Bing Peng (middle). She researches blood platelets and their lipid composition which is critical for platelet integrity and functionality. She could show, that the lipidome changes upon platelet activation. Congrats, Bing Peng!

The best scientific talk award was won by Marcus Höring (right). His work aims at the intestinal lipid metabolism and the influence of gut microbia. He made use of isotope labeled fatty acids to achieve that. Congrat, Marcus Höring!

Ronny Herzog
Dr. Ronny Herzog, Head of Software Development and IT-Infrastructure, and the awardees.

Dominik Schwudke (top left) and Robert Ahrends (bottom left) have been organizing the Lipidomics Forum since its beginning. To say thank you, we gifted both a rafting weekend. We are certain, they will have as much fun as we have with our lipid raft.

Resources

Press Release: Lipotype presents the awardees of the Lipidomics Forum 2018

Abstract book of the Lipidomics Forum 2018

Lipidomics Forum 2018

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Press Release: Lipotype and Lipoid celebrate their joint IFSCC 2018 Poster Success

Henri Deda October 9, 2018

Lipotype and Lipoid presented a joint poster featuring the core findings of their skin lipidome research at IFSCC 2018 in Munich. Overwhelmingly positive feedback resulted in placing the poster among the top 10 of all IFSCC 2018 posters.

A successful congress and a great poster
The International Federation of Societies of Cosmetic Chemists is dedicated to international cooperation in cosmetic science and technology. This year’s congress was about “Cosmetics: Science for Beauty and Lifestyle”.

Lipotype and Lipoid chose the IFSCC to present their findings as the congress focuses on exploring what modern society wants from cosmetics and dermatology. This represents both companies’ consumer oriented research best, which was confirmed on-site by the great feedback of those who visited the poster. Ultimately, the IFSCC committee chose to rank the joint poster of Lipotype and Lipoid among the top 10 of all IFSCC 2018 posters.

The project in short
Lipoid conducted this novel study to investigate skin penetration properties of dermal formulations based on hydrogenated phospholipids. For the first time, the quantitative analysis of both exogenous phospholipids and endogenous skin lipids within a single measurement was demonstrated. The results confirm the properties of hydrogenated phospholipids to penetrate and accumulate in upper epidermal layers. Based on these findings, Lipoid will conduct further investigations to improve delivery and fixation of cosmetic actives.

About Lipoid
Founded over 40 years ago, Lipoid is leading in the development and industrial production of high quality lecithin and phospholipids not only for the pharmaceutical, but also for the cosmetic and dietetic industry. Lipoid is the only company worldwide offering the whole range of natural and synthetic phospholipids in industrial scale. Environmental protection and sustainability determines the company’s strategy within all phases of the value chain. This long-standing expertise, in combination with the exceptional quality of the products enables the customers to develop and market innovative products for the benefit of the general public.

Resources

Press release: IFSCC 2018 poster success – Joint poster selected Top 10 of all IFSCC posters

IFSCC 2018 poster: The effect of saturated phospholipids on human skin as assessed by shotgun lipidomic analysis

IFSCC 2018 poster ranking

Customer reference: Lipid analysis for skin penetration properties of saturated phospholipids

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Farther than fat – Lipidomics in biotech/pharma

Henri Deda August 8, 2018

Lipotype contributed to an article about lipidomics in biotech and pharma on Technology Networks.

The article in short

Interest in lipidomics has been reignited for both, academia and industry. To cope with that, the article sums up various aspects, developments and differences in lipidomics technology. Such as Lipotype Shotgun Lipidomics technology.

Dr. Christian Klose, Head of Research and Development at Lipotype, had been interviewed to explain how to address the needs and questions of academia and industry. In the end, two researchers from academia and he give brief insights into the future of lipidomics. Both, research- and technology-wise.

Read the full article

Lipidomics in Biotech and Pharma: Farther than Fat
Ruairi J Mackenzie

About Technology Networks

Technology Networks is an online scientific publication platform. Their articles and reviews provide insights into the latest research, industry news, and technologies. Covering a wide bandwidth of scientific communities, they provide detailed coverage of analytical chemistry, life sciences, drug discovery, and neuroscience. As they enable readers to easily find reliable, digestible, and high-quality content, Technology Networks draws the attention of researchers on the science that matters to them.

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A good month for public access to research

Henri Deda July 30, 2018

July has been a great month. Three new publications with Lipotype Shotgun Lipidomics technology have been put out, and the Lipidomics Resource Center received its first major update. Read more about this!

One month – three publications

This month, three new publications with Lipotype Shotgun Lipidomics technology were published!

Paper 1: Parkinson’s disease
In Parkinson’s, excessive contacts between mitochondria and endoplasmic reticulum lead to abnormal lipid trafficking. This stops the release of “sleep” peptides affecting sleep patterns of patients long before they experience motor dysfunctions…

Paper 2: vacciness
Adjuvants like the well-established AS03 are agents in vaccines that do not provide immunity but stimulate the immune system. However, the molecular mechanism behind AS03’s adjuvant effect had yet to be fully illuminated. These new results could be applied to design novel vaccine adjuvants…

Paper 3: cancer therapeutics
Oncogenic RAS proteins must localize to the plasma membrane to act. The recently described oxanthroquinone G01 disrupts that, affects levels of some lipids and synergizes with other compounds that affect oncogenic RAS proteins. G01 could become a new anti-RAS therapeutic…

As always: access the Lipidomics Resource Center to study more publications!

The first major Lipidomics Resource Center update

We strive for scientific excellence, and therefore must hold on to the fact that all science is just as good as the research which precedes it. Therefore, we created the Lipidomics Resource Center which provides access to lipidomics publications and whitepapers to empower your research. However, that is just not enough. Therefore we added a completely new category: “products”!

There is a whole universe of research which you cannot access through reading scientific publications. And that is most of industry research. However, this type of research is reflected by product development and patents. The new category “products” gives you access to exactly this kind of hidden information.

Lipidomics is no longer a thing of the lab. It is out in the world. Now, you can learn about it!

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Job Perspective: Lipotype Lab Assistant

Henri Deda July 3, 2018

Dresden, Germany | Full/Part-time | Begin: preferably today

Are you interested in a position with competitive pay in a friendly atmosphere with career perspectives?

Is that you?

We are looking for a lab assistant who will be involved with lipid analysis and is willing to become an expert in mass spectrometry. You should be an organized person with experience in laboratory work who gets a kick out of performing reproducibly and precisely.

Lipotype – Lipidomics for a better life

Lipotype is a spin off company of the MPI of Molecular Cell Biology and Genetics in Dresden, founded by no other but Kai Simons. We are serving pharma, cosmetics and nutrition companies as well as academia worldwide. Most excitingly, we are engaged in R&D aiming at increasing global health. You can be part of a team that is moving health and prevention into unexplored territory. Join the lipid revolution!

A fantastic workplace atmosphere

Down-to-earth, driven, enthusiastic – just a few of the attributes visitors use to describe us. Our offices are cheerful with plants and other accents of green, and “strategically placed” exercise balls encourage communication. All of us contribute to Lipotype.

Please send your application to . If you have further questions, please contact Evi Kluge (). You can open and read the  PDF Document  here.

Join our Lipotype team to realize our joint vision of lipidomics for a better life!

Or at least follow us on  LinkedIn,  Twitter,  Facebook or  Google+, and  subscribe to our newsletter to stay updated on lipids and lipidomics!

New Job Offer: We are Hiring a Technical Assistant

Henri Deda June 11, 2018

Lipotype is an innovative lipidomics provider located in Dresden. We are looking for a Technical Assistant to support our start-up team. You will be responsible for sample processing for lipid analysis with mass spectrometers. Tasks include automated or manual sample preparation, lipid extraction using a robotic liquid handling station, organization of sample sets, laboratory maintenance including preparing chemicals and monitoring consumables, and associated laboratory routines.

Who you are

You are a highly organized person, accustomed to routine analytical tasks requiring high reproducibility, precision and cleanliness. Fluency in English is a prerequisite skill. Hands-on experience in automated liquid handling and high-throughput processes, as well as a practical knowledge of GLP and QM is an asset. You are trained as biological technical assistant/ medical technical assistant (biologisch-techn. / medizinisch-techn. Assistentin – BTA / MTA) or within an equivalent training program in biology, biotechnology or medicine.

Who we are

Lipotype delivers comprehensive, absolutely quantitative lipid analysis services for clinical and biological samples on a high-throughput scale. Drawing on many years of cutting edge research experience, Lipotype offers high quality lipid analysis services for a wide range of customers and applications including biomarker identification for clinical researchers, pharma and biotech companies, functional food development for the food industry, claim support for the cosmetics industry, as well as for the small-scale profiling needs of academic researchers.

Lipotype is a spin-off company from the Kai Simons and Andrej Shevchenko labs of the world-renowned Max-Planck-Institute of Molecular Cell Biology and Genetics in Dresden, Germany.

Please send your application to . If you have further questions, please contact Evi Kluge (). You can open and read the  PDF Document  here.

Join the Lipotype team to realize our joint vision of lipidomics for a better life.

Or at least follow us on  LinkedIn,  Twitter,  Facebook or  Google+, and  subscribe to our newsletter to stay updated on lipids and lipidomics!