Tag Trade Fair / Conference

First large-scale study of the genetics of human plasma lipid species

Henri Deda May 28, 2019

Understanding the genetics of lipid species offers information beyond that provided by routine lipid screening, and can help improve risk prediction and treatment. In the first large-scale study, novel lipid-associated genetic variants were identified, some of which were linked with risk for cardiovascular disease, such as heart attacks and strokes. Lipotype provided the technology to measure these lipids – Lipotype Shotgun Lipidomics.

The human blood plasma lipidome
Human plasma comprises hundreds of lipid species which differ in chemical structure and function. Many of these are known risk factors for human diseases. Advances in mass spectrometry-driven lipid analysis – lipidomics – has made it possible to study the patient lipidome to a greater extent than is possible with conventional analytical methods. Currently, however, understanding the genetic regulation of molecular lipid species is lacking. Unraveling this information could help in the personalized management of atherosclerosis and heart disease.

In light of this, this collaborative project involving centres in Finland, Germany and the USA integrated information from the lipidome, genome and phenome to answer key questions relating to the heritability of lipid species, including: Which genetic variants influence plasma levels of lipid species? How do these variants relate to disease outcomes and what is the underlying mechanisms?

The answers are…
1. Lipid species are heritable.
Lipid species heritability ranges from 10 to 54 per cent, with the highest heritability in lipids containing polyunsaturated fatty acids (PUFAs). These findings are important given renewed interest in the role of PUFAs in cardiovascular disease.

2. GWAS analyses identified 35 gene variants associated with lipids.
Using clinical outcome data, the investigators showed that 10 of these variants were associated with cardiovascular disease. In addition, 3 gene variants at the were associated with type 2 diabetes. This information could help drive the development of new treatment targets.

3. Further notes on lipid metabolism.
The study also provided clues to the underlying mechanisms of well-known lipid loci on lipid metabolism and cardiovascular disease risk.

Resources

Press Release: First large-scale study of the genetics of human plasma lipid species
Publication: Genetics of human plasma lipidome to understand lipid metabolism and its link to diseases beyond traditional lipids

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Press Release: Lipotype and Lipoid celebrate their joint IFSCC 2018 Poster Success

Henri Deda October 9, 2018

Lipotype and Lipoid presented a joint poster featuring the core findings of their skin lipidome research at IFSCC 2018 in Munich. Overwhelmingly positive feedback resulted in placing the poster among the top 10 of all IFSCC 2018 posters.

A successful congress and a great poster
The International Federation of Societies of Cosmetic Chemists is dedicated to international cooperation in cosmetic science and technology. This year’s congress was about “Cosmetics: Science for Beauty and Lifestyle”.

Lipotype and Lipoid chose the IFSCC to present their findings as the congress focuses on exploring what modern society wants from cosmetics and dermatology. This represents both companies’ consumer oriented research best, which was confirmed on-site by the great feedback of those who visited the poster. Ultimately, the IFSCC committee chose to rank the joint poster of Lipotype and Lipoid among the top 10 of all IFSCC 2018 posters.

The project in short
Lipoid conducted this novel study to investigate skin penetration properties of dermal formulations based on hydrogenated phospholipids. For the first time, the quantitative analysis of both exogenous phospholipids and endogenous skin lipids within a single measurement was demonstrated. The results confirm the properties of hydrogenated phospholipids to penetrate and accumulate in upper epidermal layers. Based on these findings, Lipoid will conduct further investigations to improve delivery and fixation of cosmetic actives.

About Lipoid
Founded over 40 years ago, Lipoid is leading in the development and industrial production of high quality lecithin and phospholipids not only for the pharmaceutical, but also for the cosmetic and dietetic industry. Lipoid is the only company worldwide offering the whole range of natural and synthetic phospholipids in industrial scale. Environmental protection and sustainability determines the company’s strategy within all phases of the value chain. This long-standing expertise, in combination with the exceptional quality of the products enables the customers to develop and market innovative products for the benefit of the general public.

Resources

Press release: IFSCC 2018 poster success – Joint poster selected Top 10 of all IFSCC posters

IFSCC 2018 poster: The effect of saturated phospholipids on human skin as assessed by shotgun lipidomic analysis

IFSCC 2018 poster ranking

Customer reference: Lipid analysis for skin penetration properties of saturated phospholipids

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Got time in September?

Henri Deda August 27, 2018

We will attend numerous national and international events in September. Take your chance to experience Lipotype, study our research and discuss with us!

Meet Lipotype at…

11. – 14. September 2018
16th ESTP, Copenhagen, Denmark
Come and visit us at our booth 7!

The 16th ESTP congress is dedicated to metabolic diseases like diabetes and how they affect neurodegenerative conditions such as Alzheimer’s.

Also, Prof. Kai Simons will hold a keynote presentation on the 12th of September at 9:00 am about “Lipid Rafts, Lipidomics and Health”. We highly recommend to listen to him.

 

18. – 19. September 2018
IFSCC 2018, Munich, Germany
We will visit the IFSCC 2018 and present the poster 216!

Exploring what modern society wants from cosmetics and dermatology – that’s what the IFSCC is all about. Besides presenting our own poster 216 in session 1, DSM’s poster 11 showcases Lipotype Shotgun Lipidomics technology, too.

 

27. – 29. September 2018
7th European Lipidomics Meeting, Leipzig, Germany
We have been invited to give a talk but will exhibit at 7th ELM, too. Visit us at our booth!

The ELM gathers the most prominent lipidomics researchers from all over the world to discuss latest technological developments. We are honored that Dr. Christian Klose has been invited as a speaker. His presentation about “Predicting obesity by machine learning based on human plasma lipidomics data” will take place on September 29th at 10:00 am.

We will staff a booth to discuss with you about latest news in lipids and lipidomics as well as recent research. Besides that, we will sponsor the best poster award.

 

If you want to schedule an individual meeting drop us a line!

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Where to meet Lipotype in June?

Henri Deda May 24, 2018

Dr Oliver Uecke and Dr Christian Klose will attend two conventions in the US in June. Besides that, Lipotype will support two academic events in the USA.

Meet Lipotype at…

18. – 21. June 2018
World Preclinical Congress, Boston, USA
Come and visit us at our booth 212!

The WPC focuses on the latest trends and technologies impacting drug discovery and translational research.

Or attend the Tech Talk of Dr. Christian Klose on the 20th of June at 9:30 am about “Shotgun Lipidomics Technology for High-Throughput Drug Discovery” on track Phenotypic Screening and Chemical Biology. We will also present a poster.

 

23. – 25. June 2018
78th Scientific Sessions of the American Diabetes Organisation, Orlando, USA
We will attend the Scientific Sessions of the ADA. Visit our booth 559!

More than 13.000 visitors attend the Scientific Sessions of the ADA to discover cutting-edge research and technology, ground-breaking studies, and advances in diabetes care.

 

If you want to schedule an individual meeting   drop us a line!

Lipotype is sponsoring the following Events

06. – 08. June 2018
37th Summer Symposium in Molecular Biology, University Park, USA
The 2018 Penn State Summer Symposium in Molecular Biology is entitled Frontiers in Metallobiochemistry and has assembled prominent researchers interested in metallobiochemistry. The symposium provides access to some truly outstanding lectures and presentations.

 

24. – 29. June 2018
FASEB: Lipid Droplets on the Move from Health to Disease, Colorado, USA
The Federation of American Societies for Experimental advances health and well-being by promoting research and education in biological and biomedical sciences through collaborative advocacy and service to our societies and their members. This FASEB’s meeting goal is to facilitate the sharing of the most up-to-date research findings and insights and to catalyze the continued growth of lipid droplet studies.

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FUTURE HEALTH – LIPIDOMICS PRESENTATION AT XPOMET

Henri Deda March 20, 2018

Dr. Christian Klose, head of research and development at Lipotype, will present at XPOMET convention this Thursday.

Starting tomorrow, the XPOMET will take place in Leipzig, Germany. The XPOMET convention focuses on interdiscliplinary and novel approaches to advance healthcare and medicine. It will feature topic-specific think tanks, discussions and the Future Health Exhibition. More than 80 speakers will present to the up to 2000 attendees.
The XPOMET is the first and only event of its kind.

Come and listen!
What – Innovative lipid analysis for industrial and academic applications
When – Thursday, 22nd March at 1:30 pm
Where – StageX Biotech & New Pharma

Download the XPOMET convention program:
XPOMET convention program 2018 (EN)

Can’t attend? Request your copy of the full presentation:
Send us an email and request your full copy of the XPOMET 2018 Lipotype presentation!

Meet the Lipotype team until the end of 2017!

Julia Schoener August 10, 2017
02.-06. December 2017
 ASCB 2017, Philadelphia, USA 
We will attend ASCB 2017! Come and visit us at our booth 1100!

Or attend the Tech Talk of Dr. Michal Surma  on the 4th of December at 8:15am about Lipotype Shotgun Lipidomics technology for comprehensive, high throughput lipid analysis located in Theater 2.

 

12.-14. November 2017
 3. Lipidomics Forum, Borstel, Germany 
We will be poster price sponsor of this lipidomics event just as last year. Dr. Ronny Herzog, Head of Software Development, will announce the winner of the best poster. 

 

06.-08. November 2017
Bio-Europe, Berlin, Germany 
Dr. Oliver Uecke, Head of Business Development and Finance and Dr. Christian Klose, Head of Research and Development, will attend the 23rd Annual International Partnering Conference. Contact us for an one-to-one Meeting!

 

23.-25. October 2017
24th Conference of the International Federation of Societies of Cosmetic Chemists, Seoul, South Korea
Lipotype will be present at the IFSCC 2017.Come and visit us at booth #24! Dr. Christian Klose, Head of Research and Development, will give a presentation about A high-throughput Shotgun Lipidomics Technology for the quantitative analysis of tape-stripped human stratum corneum lipid profiles. 

 

17.-18. October 2017
Bionection, Jena, Germany
Lipotype will be present at Bionection in Jena. Watch out for the lipidraft! 

 

If you want to schedule an individual meeting drop us a line

 

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Meet the Lipotype team in 2017!

Julia Schoener February 21, 2017
02.-06. December 2017
 ASCB 2017, Philadelphia, USA 
We will attend ASCB 2017! Come and visit us at our booth 1000!

Or attend the Tech Talk of Dr. Michal Surma on the 4th of December at 8:15 am about Lipotype Shotgun Lipidomics technology for comprehensive, high-throughput lipid analysis located in Theater 2.

 

12.-14. November 2017
 3. Lipidomics Forum, Borstel, Germany 
Dr. Michal Surma, Head of Analytical Services, will inform about skin lipidomics during a talk. 

 

06.-08. November 2017
Bio-Europe, Berlin, Germany 
We will attend the 23rd Annual International Partnering Conference. 

 

23.-25. October 2017
24th Conference of the International Federation of Societies of Cosmetic Chemists, Seoul, South Korea
Lipotype will be present at the IFSCC 2017 and we will give a presentation about A high-throughput Shotgun Lipidomics Technology for the quantitative analysis of tape-stripped human stratum corneum lipid profiles. 

 

04.-08. June 2017
 65th Conference on Mass Spectrometry and Allied Topics, Indianapolis, USA 
Dr. Christian Klose will attend the conference and will hold a poster presentation about Lipid parameters associated with obesity identified using a high-throughput Shotgun Lipidomics technology at Tuesday, the 6th of June. 

 

16.-18. May 2017
Biotechnica 2017, Hannover, Germany
Meet the Lipotype team at their booth (Hall 20, Stand A12/9) at Biotechnica 2017 in the Innovation Zone where we inform you about our Shotgun Lipidomics Technology. 

 

05.-06. April 2017
Deutsche Biotechno- logietage, Hannover, Germany
Dr. Christian Klose, Head of R&D, will participate and talk about Innovative Lipid Analysis for Cosmetics and Dermatology Applications on the second day of the conference.

 

04.-06. April 2017
in-cosmetics global, London, UK
Dr. Oliver Uecke and Tomasz Sadowski will participate to find new cooperation partners and customers to inform about our novel skin Lipidomics for cosmetic and dermatological applications. 

 

30.-31. March 2017
Workshop on the Role of Lipids in Autophagy, Copenhagen, Denmark
This workshop will take place at the Danish Cancer Society Research Center in Copenhagen. Prof. Kai Simons, Founder and CEO of Lipotype, will hold a presentation about ‘Lipidrafts to clinical Lipidomics’. We hope he will have some fruitful discussions.

 

If you want to schedule an individual meeting drop us a line

 

 

Lipotype is sponsoring the following Events:

26. February -02. March 2017
Keystone Symposia, California, USA
Lipidomics and Bioactive Lipids in Metabolism and Disease (B6)

 

10.-12. May 2017
36th Summer Symposium in Molecular Biology, Pennsylvania, USA
Metabolism: Disease Models and Model Organisms

 

Novel skin lipidomics for cosmetic and dermatological applications

Julia Schoener September 22, 2016

Lipotype GmbH, a German Max-Planck spin-off company, launched its novel Lipotype Shotgun Skin Lipidomics Technology and offers lipid analysis services for applications such as cosmetic claim support, topical drug development, efficacy testing for dermatological pharmacology and the cosmetic industry.

High-throughput skin lipidomics with ultra-broad fully quantitative coverage
Until recently, investigating skin lipidomes was not a trivial task. On one hand, the analytical method needs to have coverage broad enough to encompass the variety of skin lipids, and a throughput allowing for statistically relevant studies. On the other hand the method should be compatible with a convenient sampling technique such as tape stripping. These prerequisites are now met in the Lipotype Shotgun Skin Lipidomics Technology platform as explained by Prof. Kai Simons, CEO of Lipotype: “We offer unprecedented throughput of hundreds of samples, absolutely quantified with broad coverage of ceramides, triglycerides and other lipids, and this is all available for samples collected by super-easy tape stripping.” The development of Lipotype Skin Lipidomics was supported by the German Central Innovation Programme for SMEs.

Applications of skin lipidomics
With tools such as Lipotype Skin Lipidomics it is now easy to investigate how the healthy skin lipidome is composed, how it changes in diseases or upon intervention with a drug or a cosmetic product. This lipidomic data can be used for cosmetic claim support, topical drug development and efficacy testing. “We are excited about new possibilities to include skin lipidomics in the product development process of cosmetics companies as well as for biomarker identification for dermatology”, says Dr. Oliver Uecke, Head of Business Development and Finance at Lipotype GmbH.

Read the full press release here
Open Adobe PDF Version
 Download the Microsoft Word Version

Meet us at cosmetics360 in Paris (13.-14.10.2016)

Schedule an individual appointment and  contact us

“HIGHLIGHTS” of our novel Lipotype Shotgun Skin Lipidomics Technology

Read more here

 

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Meet the LIPOTYPE team until the end of 2016

Julia Schoener September 16, 2016
12.-13. October 2016
Cosmetics 360, Paris, France
Dr. Oliver Uecke and Tomasz Sadowski will participate cosmetics 360 to find new cooperation partners and to inform about our novel skin Lipidomics for cosmetic and dermatological applications

 

18. October 2016
Bionection 2016, Halle, Germany
Meet us at the partnering conference for technology transfer in life sciences and have a chat with Dr. Oliver Uecke, Head of BD and Finance about our recent projects and latest news.

 

20.-21. October 2016
VIB – life science research institute, Ghent and Leuven, Belgium
Meet Dr. Oliver Uecke and our scientist Dr. Christian Klose for a scientific talk held in Ghent on the 20th of October at 2pm and in Leuven on the 21st of October at 9:30am. They will inform you how Lipidomics could strengthen your research.

 

27.-29. October 2016
MPI-CBG 15th Anniversary Symposium, Dresden, Germany
Lipotype is a spin-off company from the MPI-CBG. You will meet Prof. Kai Simons, CEO of Lipotype and founding director of the MPI-CBG as well as Lipotype team members who were trained at the MPI-CBG. Dr. Christian Klose, Head of R&D will give a flash talk. We’re looking forward to catch up with old colleagues and to grow our network – Join the lipid revolution!

 

3. November 2016
Charité Berlin, Germany
Meet Lipotype’s scientist Dr. Christian Klose at the Campus Carité Mitte of Charité Univeristätsmedizin Berlin who will inform you about our ‘Lipotype Shotgun Lipidomics technology for quantitative high throughput lipid analysis’ in a scientific talk. The talk will be held at 2pm at the Center for Cardiovascular Research. 

 

13.-15. November 2016
Lipidomics Forum 2016, Dortmund, Germany
We will be poster price sponsor of this important lipidomics event in Germany. Dr. Ronny Herzog will announce the winner for the best poster on the last conference day, the 15th of November at 12:30pm.

 

29.-30. November 2016
6th Biomarker Conference, Munich, Germany
Dr. Christian Klose will attend the Conference and will give a presentation about Lipidomic parameters associated with obesity at the 29th of November at 5.45 pm.

 

03.-07. December 2016
ASCB 2016,
San Francisco, USA
We are exhibitor at the Conference. Please come and visit us at our booth 1100 to talk to our scientists.

Or attend when Dr. Christian Klose gives a Techtalk on the 6th of December at 8:15am about Lipotype Shotgun Lipidomics technology for quantitative high throughput lipid analysis located in Theater 2.

Meet the LIPOTYPE team until summer 2016:

Anja Reich April 19, 2016
26-27. April 2016
Deutsche Biotechnologie- tage,
Leipzig, Germany
We are exhibitor and sponsor of the Conference (German Biotech Days). You can meet us at there and Dr. Oliver Uecke will also give a presentation on “Innovative Lipid Analysis for Medical, Nutritonal and Academic Applications”, on April, 26th at 1:30 pm.

 

27-30. June 2016
Metabolomics, Dublin, Ireland
We are exhibitor and sponsor of the 12th Annual Conference of the Metabolomics Society. Please come and visit us at our booth (booth D2). Our Poster Presentation will be held on Tuesday, 28th of June between 5:15 pm – 6:45 pm in the Exhibit Hall. Dr. Christian Klose will inform you about Lipidomic parameters associated with obesity.