Press Release: Lipotype and Lipoid celebrate their joint IFSCC 2018 Poster Success

Lipotype and Lipoid presented a joint poster featuring the core findings of their skin lipidome research at IFSCC 2018 in Munich. Overwhelmingly positive feedback resulted in placing the poster among the top 10 of all IFSCC 2018 posters.


A successful congress and a great poster
The International Federation of Societies of Cosmetic Chemists is dedicated to international cooperation in cosmetic science and technology. This year’s congress was about “Cosmetics: Science for Beauty and Lifestyle”.

Lipotype and Lipoid chose the IFSCC to present their findings as the congress focuses on exploring what modern society wants from cosmetics and dermatology. This represents both companies’ consumer oriented research best, which was confirmed on-site by the great feedback of those who visited the poster. Ultimately, the IFSCC committee chose to rank the joint poster of Lipotype and Lipoid among the top 10 of all IFSCC 2018 posters.


The project in short
Lipoid conducted this novel study to investigate skin penetration properties of dermal formulations based on hydrogenated phospholipids. For the first time, the quantitative analysis of both exogenous phospholipids and endogenous skin lipids within a single measurement was demonstrated. The results confirm the properties of hydrogenated phospholipids to penetrate and accumulate in upper epidermal layers. Based on these findings, Lipoid will conduct further investigations to improve delivery and fixation of cosmetic actives.


About Lipoid
Founded over 40 years ago, Lipoid is leading in the development and industrial production of high quality lecithin and phospholipids not only for the pharmaceutical, but also for the cosmetic and dietetic industry. Lipoid is the only company worldwide offering the whole range of natural and synthetic phospholipids in industrial scale. Environmental protection and sustainability determines the company’s strategy within all phases of the value chain. This long-standing expertise, in combination with the exceptional quality of the products enables the customers to develop and market innovative products for the benefit of the general public.


Resources

Press release: IFSCC 2018 poster success – Joint poster selected Top 10 of all IFSCC posters

IFSCC 2018 poster: The effect of saturated phospholipids on human skin as assessed by shotgun lipidomic analysis

IFSCC 2018 poster ranking

Customer reference: Lipid analysis for skin penetration properties of saturated phospholipids


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Investigation of photodamaged dry facial skin from different ethnic groups

Lipotype put online a new skin lipidomics customer reference with Royal DSM about lipid analysis for the investigation of photodamaged dry facial skin from different ethnic groups.


The project in short
Even though decades of moisturizer development have passed, dry facial skin remains a major concern for consumers. Thus, DSM’s aim was to understand more precisely the underlying biochemistry, particularly of the maturation of the stratum corneum and its relation to facial photodamage, skin pigmentation and ethnicity. In contrast to traditional research of skin analyte composition, a more revolutionary ‘omic’ approach was applied.


What Lipotype did
With its mass spectrometry-based Shotgun Skin Lipidomics technology Lipotype delivered lipid analysis of the ceramidome, the entirety of ceramides. The results precisely highlight changes in ceramide composition and distribution which help to explain the differences in facial skin barrier function, hydration and stratum corneum maturation, but also the skin care need of the differently pigmented skin types.


About DSM
Royal DSM is a purpose-led global science-based company in Nutrition, Health and Sustainable Living. With its innovative business solutions for human nutrition, animal nutrition, personal care and aroma, medical devices, green products and applications, DSM is driving economic prosperity, environmental progress and social advances to create sustainable value. DSM’s purpose is to create brighter lives for people today and generations to come.


Find the full customer reference

Customer reference Royal DSM: lipid analysis for investigation of photodamaged dry facial skin from different ethnic groups


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Got time in September?

We will attend numerous national and international events in September. Take your chance to experience Lipotype, study our research and discuss with us!


Meet Lipotype at…

11. – 14. September 2018
16th ESTP, Copenhagen, Denmark
Come and visit us at our booth 7!

The 16th ESTP congress is dedicated to metabolic diseases like diabetes and how they affect neurodegenerative conditions such as Alzheimer’s.

Also, Prof. Kai Simons will hold a keynote presentation on the 12th of September at 9:00 am about “Lipid Rafts, Lipidomics and Health”. We highly recommend to listen to him.

 

18. – 19. September 2018
IFSCC 2018, Munich, Germany
We will visit the IFSCC 2018 and present the poster 216!

Exploring what modern society wants from cosmetics and dermatology – that’s what the IFSCC is all about. Besides presenting our own poster 216 in session 1, DSM’s poster 11 showcases Lipotype Shotgun Lipidomics technology, too.

 

27. – 29. September 2018
We have been invited to give a talk but will exhibit at 7th ELM, too. Visit us at our booth!

The ELM gathers the most prominent lipidomics researchers from all over the world to discuss latest technological developments. We are honored that Dr. Christian Klose has been invited as a speaker. His presentation about “Predicting obesity by machine learning based on human plasma lipidomics data” will take place on September 29th at 10:00 am.

We will staff a booth to discuss with you about latest news in lipids and lipidomics as well as recent research. Besides that, we will sponsor the best poster award.

 

If you want to schedule an individual meeting drop us a line!


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Farther than fat – Lipidomics in biotech/pharma

Lipotype contributed to an article about lipidomics in biotech and pharma on Technology Networks.


The article in short

Interest in lipidomics has been reignited for both, academia and industry. To cope with that, the article sums up various aspects, developments and differences in lipidomics technology. Such as Lipotype Shotgun Lipidomics technology.

Dr. Christian Klose, Head of Research and Development at Lipotype, had been interviewed to explain how to address the needs and questions of academia and industry. In the end, two researchers from academia and he give brief insights into the future of lipidomics. Both, research- and technology-wise.


Read the full article

Lipidomics in Biotech and Pharma: Farther than Fat
Ruairi J Mackenzie


About Technology Networks

Technology Networks is an online scientific publication platform. Their articles and reviews provide insights into the latest research, industry news, and technologies. Covering a wide bandwidth of scientific communities, they provide detailed coverage of analytical chemistry, life sciences, drug discovery, and neuroscience. As they enable readers to easily find reliable, digestible, and high-quality content, Technology Networks draws the attention of researchers on the science that matters to them.


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A good month for public access to research

July has been a great month. Three new publications with Lipotype Shotgun Lipidomics technology have been put out, and the Lipidomics Resource Center received its first major update. Read more about this!


One month – three publications

This month, three new publications with Lipotype Shotgun Lipidomics technology were published!

Paper 1: Parkinson’s disease
In Parkinson’s, excessive contacts between mitochondria and endoplasmic reticulum lead to abnormal lipid trafficking. This stops the release of “sleep” peptides affecting sleep patterns of patients long before they experience motor dysfunctions

Paper 2: vacciness
Adjuvants like the well-established AS03 are agents in vaccines that do not provide immunity but stimulate the immune system. However, the molecular mechanism behind AS03’s adjuvant effect had yet to be fully illuminated. These new results could be applied to design novel vaccine adjuvants

Paper 3: cancer therapeutics
Oncogenic RAS proteins must localize to the plasma membrane to act. The recently described oxanthroquinone G01 disrupts that, affects levels of some lipids and synergizes with other compounds that affect oncogenic RAS proteins. G01 could become a new anti-RAS therapeutic

As always: access the Lipidomics Resource Center to study more publications!


The first major Lipidomics Resource Center update

We strive for scientific excellence, and therefore must hold on to the fact that all science is just as good as the research which precedes it. Therefore, we created the Lipidomics Resource Center which provides access to lipidomics publications and whitepapers to empower your research. However, that is just not enough. Therefore we added a completely new category: “products”!

There is a whole universe of research which you cannot access through reading scientific publications. And that is most of industry research. However, this type of research is reflected by product development and patents. The new category “products” gives you access to exactly this kind of hidden information.

Lipidomics is no longer a thing of the lab. It is out in the world. Now, you can learn about it!


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Parkinson’s Disease, Fruit Flies and Lipotype

What happened

Do fruit flies suffer from Parkinson’s? Not exactly. But patients who suffer from this neurological disease experience disturbed sleep patterns long before motor dysfunctions. This can be modelled in fruit flies. Researchers from the Netherlands and Germany showed that excessive contacts between mitochondria and endoplasmic reticulum in Parkinson’s flies lead to abnormal lipid trafficking. This prevents the release of “sleep” neuropeptides, which affects sleep patterns.

Lipotype performed lipid analysis on fruit fly heads and various organelles. The results clearly supported the researchers’ hypothesis: in Parkinson’s fruit flies the lipid PtdSer is transferred from the endoplasmic reticulum to the mitochondria, and converted to PtdEtn at a higher rate, when compared with healthy flies. This was proven through Lipotype Shotgun Lipidomics technology.


Read the full publication

ER Lipid Defects in Neuropeptidergic Neurons Impair Sleep Patterns in Parkinson’s Disease – Neuron, 2018
Jorge S Valadas, Giovanni Esposito, Dirk Vandekerkhove, Katarzyna Miskiewicz, Liesbeth Deaulmerie, Susanna Raitano, Philip Seibler, Christine Klein, Patrik Verstreken


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Job Perspective: Lipotype Lab Assistant

Dresden, Germany | Full/Part-time | Begin: preferably today

Are you interested in a position with competitive pay in a friendly atmosphere with career perspectives?


Is that you?

We are looking for a lab assistant who will be involved with lipid analysis and is willing to become an expert in mass spectrometry. You should be an organized person with experience in laboratory work who gets a kick out of performing reproducibly and precisely.


Lipotype – Lipidomics for a better life

Lipotype is a spin off company of the MPI of Molecular Cell Biology and Genetics in Dresden, founded by no other but Kai Simons. We are serving pharma, cosmetics and nutrition companies as well as academia worldwide. Most excitingly, we are engaged in R&D aiming at increasing global health. You can be part of a team that is moving health and prevention into unexplored territory. Join the lipid revolution!


A fantastic workplace atmosphere

Down-to-earth, driven, enthusiastic – just a few of the attributes visitors use to describe us. Our offices are cheerful with plants and other accents of green, and “strategically placed” exercise balls encourage communication. All of us contribute to Lipotype.


Apply now

Please send your application to career@lipotype.com. If you have further questions, please contact Evi Kluge (kluge@lipotype.com). You can open and read the  PDF Document  here.


Join our Lipotype team to realize our joint vision of lipidomics for a better life!

Or at least follow us on  LinkedIn,  Twitter,  Facebook or  Google+, and  subscribe to our newsletter to stay updated on lipids and lipidomics!

lipid analysis for skin penetration properties of saturated phospholipids

Lipotype put online a new skin lipidomics customer reference with Lipoid about lipid analysis for skin penetration properties of saturated phospholipids.


What is skin lipidomics

The physiology of skin derives from its structure and composition of its topmost layer, where cells are glued together by lipids. Their composition is influenced by natural conditions, such as age and gender, but also various diseases. Lipotype Skin Shotgun Lipidomics Technology provides the tools to investigate how the healthy skin lipidome is composed, how it changes in diseases or upon intervention with a drug or a cosmetic product. This lipidomic data can be used for cosmetic claim support, topical drug development and personalized cosmetics.


The project in short

Lipoid conducted this novel study to investigate skin penetration properties of dermal formulations based on hydrogenated phospholipids. Common to all topically used phospholipids is their ability to interact with skin structures and the similarity to epidermal lipids. For the first time, the quantitative analysis of both exogenous phospholipids and endogenous skin lipids within a single measurement was demonstrated. The results confirm the properties of hydrogenated phospholipids to penetrate and accumulate in upper epidermal layers. Lipotype performed lipid analysis of phospholipids of an applied formulation, especially focusing on phosphatidylcholine.


About Lipoid

Phospholipids are widespread functional ingredients, not only in pharmaceutical formulations, but in cosmetic and dietetic products as well. Lipoid was the first to offer a wide variety of phospholipids for use in the production of drug products. Today, the majority of approved drugs containing phospholipids are prepared using raw materials from Lipoid. Based on these findings, Lipoid will conduct further investigations to improve delivery and fixation of an active pharmaceutical ingredient.


Find the full customer reference

Customer reference Lipoid: lipid analysis for skin penetration properties of saturated phospholipids


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New Job Offer: We are Hiring a Technical Assistant

Lipotype is an innovative lipidomics provider located in Dresden. We are looking for a Technical Assistant to support our start-up team. You will be responsible for sample processing for lipid analysis with mass spectrometers. Tasks include automated or manual sample preparation, lipid extraction using a robotic liquid handling station, organization of sample sets, laboratory maintenance including preparing chemicals and monitoring consumables, and associated laboratory routines.


Who you are

You are a highly organized person, accustomed to routine analytical tasks requiring high reproducibility, precision and cleanliness. Fluency in English is a prerequisite skill. Hands-on experience in automated liquid handling and high-throughput processes, as well as a practical knowledge of GLP and QM is an asset. You are trained as biological technical assistant/ medical technical assistant (biologisch-techn. / medizinisch-techn. Assistentin – BTA / MTA) or within an equivalent training program in biology, biotechnology or medicine.


Who we are

Lipotype delivers comprehensive, absolutely quantitative lipid analysis services for clinical and biological samples on a high-throughput scale. Drawing on many years of cutting edge research experience, Lipotype offers high quality lipid analysis services for a wide range of customers and applications including biomarker identification for clinical researchers, pharma and biotech companies, functional food development for the food industry, claim support for the cosmetics industry, as well as for the small-scale profiling needs of academic researchers.

Lipotype is a spin-off company from the Kai Simons and Andrej Shevchenko labs of the world-renowned Max-Planck-Institute of Molecular Cell Biology and Genetics in Dresden, Germany.


Apply now

Please send your application to career@lipotype.com. If you have further questions, please contact Evi Kluge (kluge@lipotype.com). You can open and read the  PDF Document  here.


Join the Lipotype team to realize our joint vision of lipidomics for a better life.

Or at least follow us on  LinkedIn,  Twitter,  Facebook or  Google+, and  subscribe to our newsletter to stay updated on lipids and lipidomics!

How lipids change biological research

Lipotype published a German article about lipidomics in the LABO magazine.


About LABO magazine

The German magazine LABO publishes application-oriented and competent articles about products and services for industry and research laboratories. With its writings, it connects people and markets, providing precisely all necessary information for daily work in the area of analytics and lab technology.


The article in short

The article sums up the recent developments and changes in lipids and lipidomics research and provides a brief summary of Lipotype’s services and history. Finally, it focuses on the conclusion that lipids may have a strong impact on the not so far future of medicare and personalized medicine. This opinion piece in the end is accompanied by two examples of current research publications.


Read the full article

Wie Lipide die biologische Forschung verändern – Die Revolution der Fette
Christian Klose, Henri Deda


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