Lipotype’s customer Lyomark Pharma announces partnership

Lyomark Pharma, a customer of Lipotype, announces a partnership with Aerogen Pharma to develop an inhaled surfactant for the treatment of preterm infants with Respiratory Distress Syndrome (RDS). At the same time clinical trials with the new delivery system have been initiated and the first patients have been recruited. Read more in the press release of Lyomark and Aerogen:


Read more in the press release of Lyomark and Aerogen here:
Aerogen Pharma and Lyomark Pharma partner to develop inhaled surfactant, begin a Phase 2 clinical trial

Meet the Lipotype team until the end of 2017!

02.-06. December 2017
 ASCB 2017, Philadelphia, USA 
We will attend ASCB 2017! Come and visit us at our booth 1100!

Or attend the Tech Talk of Dr. Michal Surma  on the 4th of December at 8:15am about Lipotype Shotgun Lipidomics technology for comprehensive, high throughput lipid analysis located in Theater 2.

 

12.-14. November 2017
 3. Lipidomics Forum, Borstel, Germany 
We will be poster price sponsor of this lipidomics event just as last year. Dr. Ronny Herzog, Head of Software Development, will announce the winner of the best poster. 

 

06.-08. November 2017
Bio-Europe, Berlin, Germany 
Dr. Oliver Uecke, Head of Business Development and Finance and Dr. Christian Klose, Head of Research and Development, will attend the 23rd Annual International Partnering Conference. Contact us for an one-to-one Meeting!

 

23.-25. October 2017
24th Conference of the International Federation of Societies of Cosmetic Chemists, Seoul, South Korea
Lipotype will be present at the IFSCC 2017.Come and visit us at booth #24! On the 25th of October 2017, Dr. Christian Klose, Head of Research and Development, will give a presentation about Innovative Lipid Analysis for Cosmetics and Dermatology Applications at 10:50 am. 

 

If you want to schedule an individual meeting drop us a line

Lipid analysis for early stages of drug discovery: Customer Reference Flagship VentureLabs

Lipotype performed lipid analysis for Flagship VentureLabs with the aim to better understand molecular compositions of chondrisomes, pharmaceutically active derivatives of mitochondria. The research of Flagship VentureLabs is on novel ways of preparation of chondrisomes that have beneficial structural characteristics, yield, concentration, stability, viability, integrity, or function. The lipidomic results facilitated the characterization of isolated chondrisomes in order to evaluate their quality and subsequently were used to file a recently published patent application.

Read more  


Read the patent application here
Methods and Compositions of Chondrisomes – United States Patent Application 20170151287, 2017
G A Von Maltzahn, J M Milwid, M Mee, J R Rubens, D Chess, K Trudeau, K Mahdaviani, J Feala

Skin lipidomics: a tool for understanding skin aging at the molecular level

Lipotype published in SOFW Journal about skin lipidomics to better understand skin aging

The lipid composition of human skin is essential for its function; however the simultaneous quantification of a wide range of skin lipids, belonging to both stratum corneum and sebum, is not trivial. Recently we developed a new, “shotgun” mass spectrometry-based method characterized by a broad coverage of lipids, absolute quantitation, high reproducibility and high-throughput providing comprehensive insight into skin lipid composition [1].

We applied this method in a large-scale study of natural lipid variability of human skin. In this study we analyzed samples from 104 individuals of both sexes of different ages. We discovered gradual changes in the skin lipidome correlated with age but no sex-specific differences. Our novel method enables detailed and broad insights into skin lipidomes, both in terms of lipidome coverage and sample number. Therefore, skin shotgun lipidomics has the potential to become useful in studies related to skin aging and anti-aging product claims support.

Read more: 
Click her to read the full article in SOFW Journal


Learn more about Lipotype Skin Lipidomics
 Download our White Paper

[1] Large-scale human skin lipidomics by quantitative, high-throughput shotgun mass spectrometry – Scientific Reports, 2017
Tomasz Sadowski, Christian Klose, Mathias J. Gerl, Anna Wójcik-MaciejewiczRonny HerzogKai SimonsAdam Reich, Michal A. Surma

Meet the Lipotype team until the end of 2017!

02.-06. December 2017
 ASCB 2017, Philadelphia, USA 
We will attend ASCB 2017! Come and visit us at our booth 1100!

Or attend the Tech Talk of Dr. Michal Surma  on the 4th of December at 8:15am about Lipotype Shotgun Lipidomics technology for comprehensive, high throughput lipid analysis located in Theater 2.

 

12.-14. November 2017
 3. Lipidomics Forum, Borstel, Germany 
We will be poster price sponsor of this lipidomics event just as last year. Dr. Ronny Herzog, Head of Software Development, will announce the winner of the best poster. 

 

06.-08. November 2017
Bio-Europe, Berlin, Germany 
Dr. Oliver Uecke, Head of Business Development and Finance and Dr. Christian Klose, Head of Research and Development, will attend the 23rd Annual International Partnering Conference. Contact us for an one-to-one Meeting!

 

23.-25. October 2017
24th Conference of the International Federation of Societies of Cosmetic Chemists, Seoul, South Korea
Lipotype will be present at the IFSCC 2017.Come and visit us at booth #24! Dr. Christian Klose, Head of Research and Development, will give a presentation about A high-throughput Shotgun Lipidomics Technology for the quantitative analysis of tape-stripped human stratum corneum lipid profiles

 

17.-18. October 2017
Bionection, Jena, Germany
Lipotype will be present at Bionection in Jena. Watch out for the lipidraft

 

If you want to schedule an individual meeting drop us a line

 

Lipotype analyzed Munich MIDY Pig Biobank samples for multi-omics studies of organ crosstalk in diabetes

Lipotype lipidomics was part of a wider study of samples from Munich MIDY Pig Biobank – an animal model to study poorly controlled diabetes mellitus. Lipidomic data clearly separated MIDY and WT samples. The detailed characterization of these samples will help to establish an unique resource for systematic studies of organ crosstalk in diabetes in a multi-organ, multi-omics dimension.

 

Read the whole publication here:

The Munich MIDY Pig Biobank – A unique resourse for studying organ crosstalk in diabetes – Molecular Metabolism, 2017
Andreas Blutke et. al.

Lipids in diabetes type 2 research

The Paul Langerhans Institute Dresden (PLID) tackles diabetes by applying lipidomics analysis form Lipotype.


Lipids and diabetes
The PLID frequently applies Lipotype Shotgun Lipidomics services for their molecular diabetes research to step by step reveal lipid-associated cellular processes. Their investigations lead to the definition of molecular lipid signatures that tell about the development on non-diabetic to diabetes type 2 and progression towards diabetes complications.

Furthermore, the PLID is a project partner of Lipotype within the RHAPSODY consortium, an IMI project combining new and existing data to refine diagnosis, promote prevention and support drug discovery for personalized management of diabetes.


About the PLID
In type 1 and type 2 diabetes, destroyed or impaired beta cells cause an elevated blood sugar level. PLID scientists are working on deciphering the mechanisms that lead to the destruction and/or functional impairment of beta cells and are also trying to develop new approaches to replace damaged or destroyed beta cells.

The PLID is a founding partner of the German Center for Diabetes Research (DZD).


Resources

1 – Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus


Follow us on LinkedIn, Twitter or Facebook, and subscribe to our newsletter to stay updated on lipids and lipidomics!

Release of White Paper: Big data lipidomics for lipid biomarker identification

Lipidomics is the large-scale investigation of lipids in biological systems. Venturing into the analysis of large dataset, with potential thousands of lipidomes, by advanced multiparametric statistical approaches is a challenging endeavour. We established algorithms and a full set of methods tailored to quantitative lipid data. This allows to perform statistical analysis and enrichment analysis in order to identify lipid biomarkers. In our recently published white paper a cohort of healthy subjects is compared with a cohort of diseased subjects. The result is a lipid signature that discriminates healthy from disease. Those could then potentially be of use for disease stratification or diagnosis by means of predictive modelling (machine learning). In this white paper, we will guide you through the data analysis process for lipid biomarkers.   Read more


Learn more about Big Data Lipidomics and get the White Paper.


Follow us on  LinkedIn Twitter or  subscribe to our newsletter

Metabolomics meets systems biology

Read the Technology Feature by SCIENCE about “Big data, big picture: Metabolomics meets systems biology” in which companies and scientists explain how they use metabolomics to understand system biology. Lipotype’s CEO, Kai Simons, explains why lipidomics is an important part of metabolomics and that lipids can be quantified which tells about the state of a cell or tissue:

Click here to read the full article

 

Genetic Testing and Analysis

source: www.sciencemag.org