Case Studies
A cell contains thousands of lipids. Lipidomics reports the precise lipid composition of a sample to fuel research and progress in all biology related fields.
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Case StudyLipidomics of lipid droplets in health and disease
Lipotype
Lipid droplets and their lipid content are crucial for the healthy functioning of the organism.
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Case StudyMultiorgan lipidomics and fasting glycemia
Swiss Institute of Bioinformatics
Lipid profiles of adipose tissue, muscle, and liver and glucose blood level in fasting mice.
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Case StudyThe role of lipid droplets in ischemic stroke
Universitätsmedizin Göttingen
The role of lipid metabolism in post-stroke inflammation development and resolution.
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Case StudyLipid structural flexibility and lipid droplets
KRICT
The structural flexibility of lipids affects their migration into lipid droplets.
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Case StudyStarvation and lipid metabolism
Centre for Genomic Regulation
TANGO2 plays a role in lipid metabolism and affects cellular organization during starvation.
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Case StudyPhospholipidomics of a murine eye
University of Florida
Phosphoinositide lipids show area-specific distribution in the rods of a mouse retina.
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Case StudyDietary fatty acids influence the cell membrane
University of Virginia
PUFAs coming from diet incorporate into the plasma membrane and affect its biophysical properties.
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Case StudyGrowth temperature influences membrane lipids
University of Michigan
Temperature conditions affect the lipid composition of giant plasma membrane vesicles obtained from cells.
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Case StudyLipids & kidney disease in diabetes
Heidelberg University Hospital
Modifying dietary fatty acids composition may protect the kidney in patients with diabetes.
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Case StudyLipid metabolism impacts remyelination
Technical University of Munich
Remyelination requires orchestrated lipid droplets formation and cholesterol esterification by microglia.
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Case StudyT cell function & lipid metabolism
University College London
Activation of LXR in T helper cells alters lipid metabolism, reduces membrane order, and modifies the immune response.
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Case StudyCardiolipin synthesis & protein import during mtUPR
Albert-Ludwigs-Universität Freiburg
The mtUPR in yeast exhibits an initial increase in protein import, which is accompanied by cardiolipin synthesis and remodeling.
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Case StudyChain length impacts membrane fluidity
Utrecht University
Yeast adapts to the absence of phosphatidylcholine by changing lipid composition to restore membrane fluidity.
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Case StudyCancer, hypoxia & mitochondria lipids
The University of Hong Kong
The enzyme PTPMT1, which synthesizes the mitochondrial lipid cardiolipin, helps cancer cells adapt to hypoxia.
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Case StudyExosome characterization for targeted drug delivery
Roche
Exosomes may be useful for targeted drug delivery. Proteomic & lipidomic characterization are required for this goal.
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