Case Studies
A cell contains thousands of lipids. Lipidomics reports the precise lipid composition of a sample to fuel research and progress in all biology related fields.
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Case StudyInsulin sensitivity & circadian lipid metabolism
German Institute of Human Nutrition
The plasma lipid profile depends on meal timing and composition and is associated with insulin sensitivity.
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Case StudyCancer, hypoxia & mitochondria lipids
The University of Hong Kong
The enzyme PTPMT1, which synthesizes the mitochondrial lipid cardiolipin, helps cancer cells adapt to hypoxia.
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Case StudyMultiomics profiling of Alzheimer’s disease
Nestlé Health Science
Multiomics analyses with lipidomics reveal molecular pathways in Alzheimer’s disease to improve predictive power.
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Case StudyClinical indicators of metabolic obesity
Finnish Institute for Health and Welfare
Metabolic indicators in the plasma lipidome can classify obesity status more accurately than standard metrics.
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Case StudyVariability of skin lipidomics profiles
Wrocław Medical University
Skin lipid composition impacts skin health and can be studied via lipidomics but sex, age and, sample depth affect the data.
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Case StudyCardiac lipid metabolism in heart failure
Charité Universitätsmedizin
Heart failure changes lipid metabolism in cardiac tissue of mice. The altered lipid profile can be confirmed in human plasma.
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Case StudyMultiomics analysis in type 1 diabetes research
Ludwig-Maximilians-Universität München
Combined transcriptomic, proteomic, lipidomic, & metabolomic analyses can characterize the molecular basis of diabetes.
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Case StudyExosome characterization for targeted drug delivery
Roche
Exosomes may be useful for targeted drug delivery. Proteomic & lipidomic characterization are required for this goal.
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Case StudyBreast cancer & phospholipid metabolism
UTHealth
Breast cancer phospholipid metabolism is a powerful target for new therapies, especially against triple-negative breast cancer.
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Case StudyLipid profiles of neurons & glia cells
DZNE
The brain of mammals is the second-most lipid-rich organ. Lipid analysis of neural cells helps understand its complex structure.
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Case StudyLipid biomarkers for multiple sclerosis
DZNE
Diagnosing multiple sclerosis is difficult. Lipid markers can support diagnosis and treatment of the neuroinflammatory disease.
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Case StudyMultiomics in cardiovascular disease research
Institute for Molecular Medicine Finland
A population health study examined the relationships between genotypes, the plasma lipidome, and cardiovascular diseases.
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Case StudySkin pigmentation and ceramide content
DSM
Skin biology is central to develop reliable moisturizers, but molecular analysis of the skin has been lacking.
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Case StudyMulti resistant bacteria & phospholipids
Helmholtz Centre for Infection Research
The development of new antibiotics alone is not believed to stop multi resistant bacteria. A new strategy is emerging.
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Case StudyLipid-based adjuvants in vaccine development
Université Libre de Bruxelles
Adjuvants are added to vaccines to boost their efficiency, but the underlying molecular mechanisms used to be poorly understood.
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