Case Studies
A cell contains thousands of lipids. Lipidomics reports the precise lipid composition of a sample to fuel research and progress in all biology related fields.
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Case StudyPhospholipid remodelling in fatty liver disease
AstraZeneca
Changes in phosphatidylethanolamine composition influence the development of NAFLD and NASH
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Case StudyMultiorgan lipidomics and fasting glycemia
Swiss Institute of Bioinformatics
Lipid profiles of adipose tissue, muscle, and liver and glucose blood level in fasting mice.
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Case StudyGanglioside lipidomics in CNS developmental myelination
DZNE
Researchers developed a method to quantify the full ganglioside lipidome in CNS during various developmental stages.
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Case StudyStarvation and lipid metabolism
Centre for Genomic Regulation
TANGO2 plays a role in lipid metabolism and affects cellular organization during starvation.
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Case StudyPhospholipidomics of a murine eye
University of Florida
Phosphoinositide lipids show area-specific distribution in the rods of a mouse retina.
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Case StudyAging, gut microbiome, and lipid metabolism
Nestlé Health Science
Age-related gut microbiome changes are reflected in serum lipidome.
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Case StudyLipidomics of extracellular vesicle subtypes
University of Basel, Pharmaceutical Sciences
Lipidomics analysis supports the preparation and analysis of nano plasma membrane vesicles (nPMVs).
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Case StudyLipid metabolism genes
MPI-CBG
CRISPR/Cas9-based gene knockouts allow for a better understanding of lipid metabolic pathways.
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Case StudyGrowth temperature influences membrane lipids
University of Michigan
Temperature conditions affect the lipid composition of giant plasma membrane vesicles obtained from cells.
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Case StudyChain length impacts membrane fluidity
Utrecht University
Yeast adapts to the absence of phosphatidylcholine by changing lipid composition to restore membrane fluidity.
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Case StudyCardiac lipid metabolism in heart failure
Charité Universitätsmedizin
Heart failure changes lipid metabolism in cardiac tissue of mice. The altered lipid profile can be confirmed in human plasma.
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Case StudyLipid profiles of neurons & glia cells
DZNE
The brain of mammals is the second-most lipid-rich organ. Lipid analysis of neural cells helps understand its complex structure.
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