Our colleagues conducted a study involving pancreatic islets from living donors, encompassing a full range of glycemic conditions from normoglycemia to type 2 diabetes (T2D). Their findings reveal significant differences in the transcriptomic and proteomic profiles of islets from T2D patients compared to non-diabetic individuals.
Moreover, by integrating islet transcriptomics with blood plasma lipidomics, researchers investigated the interplay between gene expression and lipid levels related to HbA1c. This approach holds promise for identifying key prognostic markers for T2D.
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