Case Studies

CRISPR/Cas9-based gene knockouts allow for a better understanding of lipid metabolic pathways.

Lipid profiling differentiates between metabolically healthy and unhealthy obesity.

Regulating fatty acid metabolism using lipases could be beneficial in Parkinson’s disease treatment.

Lipidomics risk score allows to accurately measure the risk of diabetes and cardiovascular disease development

Temperature conditions affect the lipid composition of giant plasma membrane vesicles obtained from cells.

Endoplasmic reticulum stress is a process that is involved in the development of many diseases.

Plasma lipidomics analysis is a promising tool for a differential diagnosis of various atherosclerosis-related vascular diseases.

Modifying dietary fatty acids composition may protect the kidney in patients with diabetes.

Application of a moisturizing body lotion to dry skin improves barrier properties and alters ceramide profile and skin microbiome.

Remyelination requires orchestrated lipid droplets formation and cholesterol esterification by microglia.

Activation of LXR in T helper cells alters lipid metabolism, reduces membrane order, and modifies the immune response.

Multiomics analyses of well-studied diseases can reveal molecular pathways, identify biomarkers, and improve predictive models.

LDLR expression influences ovarian cancer cells’ lipid profiles and sensitivity to platinum-based chemotherapy.

The mtUPR in yeast exhibits an initial increase in protein import, which is accompanied by cardiolipin synthesis and remodeling.

Yeast adapts to the absence of phosphatidylcholine by changing lipid composition to restore membrane fluidity.