Articles & Webinars
A cell contains thousands of lipids. Lipidomics reports the precise lipid composition of a sample to fuel research and progress in all biology related fields.
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Article
Cardiolipin synthesis & protein import during mtUPR
The mtUPR in yeast exhibits an initial increase in protein import, which is accompanied by cardiolipin synthesis and remodeling.
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Chain length impacts membrane fluidity
Yeast adapts to the absence of phosphatidylcholine by changing lipid composition to restore membrane fluidity.
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Anorexia, refeeding & lipid metabolism
The plasma lipidome in anorexia patients before and after refeeding therapy exhibits dysregulated lipid metabolism.
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Insulin sensitivity & circadian lipid metabolism
The plasma lipid profile depends on meal timing and composition and is associated with insulin sensitivity.
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Cancer, hypoxia & mitochondria lipids
The enzyme PTPMT1, which synthesizes the mitochondrial lipid cardiolipin, helps cancer cells adapt to hypoxia.
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Multiomics profiling of Alzheimer’s disease
Multiomics analyses with lipidomics reveal molecular pathways in Alzheimer’s disease to improve predictive power.
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Clinical indicators of metabolic obesity
Metabolic indicators in the plasma lipidome can classify obesity status more accurately than standard metrics.
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Variability of skin lipidomics profiles
Skin lipid composition impacts skin health and can be studied via lipidomics but sex, age and, sample depth affect the data.
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Cardiac lipid metabolism in heart failure
Heart failure changes lipid metabolism in cardiac tissue of mice. The altered lipid profile can be confirmed in human plasma.
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Multiomics analysis in type 1 diabetes research
Combined transcriptomic, proteomic, lipidomic, & metabolomic analyses can characterize the molecular basis of diabetes.
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Exosome characterization for targeted drug delivery
Exosomes may be useful for targeted drug delivery. Proteomic & lipidomic characterization are required for this goal.
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Breast cancer & phospholipid metabolism
Breast cancer phospholipid metabolism is a powerful target for new therapies, especially against triple-negative breast cancer.
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