Oxidized octadecaenoic acids belong to the group of octadecanoids within the fatty acyls. Their structure is based on octadecanoic acid, an eighteen carbon atoms long hydrocarbon chain with a carboxyl group. The chain contains one double bond, from which their name derives. Oxidized octadecaenoic acids may further encompass multiple oxygen containing substituents.
The biological role of oxidized octadecaenoic acids is associated with modifying inflammatory responses. For example, they increase sensitivity to inflammatory pain. Oxidized octadecaenoic acids synthesis is increased during cold temperatures to stimulate activity of brown adipose tissue and thus body temperature. Dysregulated oxidized octadecaenoic acids levels have been found in pulmonary diseases.
Here you can read more about the analysis of oxidized octadecaenoic acids performed at Lipotype:
#FattyAcyls #lipid #lipidomics #MassSpectrometry #OxidizedOctadecaenoicAcid
