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Ergosterol

We provide MS-based lipid analysis of Ergosterol in yeast samples and deliver results in as little as two weeks.

Details

About the structure and biological function of Erg

Structure. Ergosterol (Erg) is a type of sterol lipid. Similar to cholesterol, the structure of ergosterol consists of four linked hydrocarbon rings, the steroid structure. A hydrocarbon tail is linked to one end of the steroid, a hydroxyl group linked to the other end.

Function. Ergosterol serves an important structural role in the cell membrane of fungi and also forms lipid rafts – similar to cholesterol in animal cells. Under conditions of stress, the sterol concentration of the cell membrane can change rapidly. It also has multiple functions in growth regulation and is a precursor to vitamin D2. Further, a range of antifungal drugs targets ergosterol by either binding to it in the cell membrane to cause cellular leakage, or by preventing ergosterol synthesis.

GENERAL STRUCTURE
Erg

General molecular structure of ergosterol.

Erg lipidomics analysis with
Lipotype

Structural detailsclass level
Variants identified 1
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-4 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Yeast includes:
Erg, EE, CDP-DAG, IPC, MIPC, M(IP)2C

GENERAL STRUCTURE
Erg

General molecular structure of ergosterol.

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