About the structure and biological function of Erg
Structure. Ergosterol (Erg) is a type of sterol lipid. Similar to cholesterol, the structure of ergosterol consists of four linked hydrocarbon rings, the steroid structure. A hydrocarbon tail is linked to one end of the steroid, a hydroxyl group linked to the other end.
Ergosterol is the major sterol lipid in fungi and also some unicellular eukaryotes. On a subcellular level, it is enriched in the cell membrane.
Function. Ergosterol serves an important structural role in the cell membrane of fungi and also forms lipid rafts – similar to cholesterol in animal cells. Under conditions of stress, the sterol concentration of the cell membrane can change rapidly. It also has multiple functions in growth regulation and is a precursor to vitamin D2. Further, a range of antifungal drugs targets ergosterol by either binding to it in the cell membrane to cause cellular leakage, or by preventing ergosterol synthesis.
Erg lipidomics analysis with
|Structural details||class level|
|Device||Q Exactive Orbitrap (280.000 Res)|
|Delivery time||2-4 weeks|
|Lipidomics data||pmol & mol%|
Erg, EE, CDP-DAG, IPC, MIPC, M(IP)2C
Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.
You want to inquire lipid analysis for your project or ask questions about Lipotype Shotgun Lipidomics? Please use the contact form below!