Ferroptosis is a regulated form of cell death that is associated with the accumulation of lipid hydroperoxides and reactive oxygen species that break down fats in cellular membranes.
Ferroptosis plays a role in various diseases, including neurodegeneration, cardiovascular diseases, kidney disorders, and various types of cancer.
The mice fed with tung oil showed slowed growth and spreading of breast tumors. Additionally, the tumors showed changes in gene expression consistent with ferroptosis. The results provide insight into ferroptosis regulation and offer a potential therapeutic approach to cancer treatments.
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#research #lipid #lipidomics #LipidMetabolism #lipotype #lipidome #MassSpectrometry #ferroptosis
