The mouse brain serves as a powerful animal model to study the human brain, its diseases, and mental disorders. The genes responsible for building and operating both the mouse and human brain are highly concordant.
The cellular architecture of the human and mouse brain tissues is well-conserved. They are organized in a very similar fashion and contain a comparable diversity of cell types.
Researchers generated a cell-type-resolved lipidomic profile of the mouse brain – in order to acquire a basic yet distinctive dataset for further neurobiological research. They applied lipidomics analysis to differentiate the lipid composition of neurons and different glia cell types, including astrocytes, oligodendrocytes, and microglia.
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