About the structure and biological function of TAG
Structure. Triacylglycerols (triglycerides, TAG, or TG) are a type of glycerolipids. Their structure consists of a glycerol backbone linked to three fatty acids. The fatty acids can be of variable length, hydroxylated, and contain double bonds.
Occurrence.Triacylglycerols are found mainly in eukaryotic cells and are elevated in animal adipose tissue as well as fruits and seeds of plants. On a subcellular level, they are enriched in lipid droplets.
Function. Triacylglycerols are a great source of energy in eukaryotes. Commercially important fats and oils of animal and plant origin consist almost exclusively of triacylglycerols. They also serve as pool for structural and bioactive fatty acids. The excessive accumulation of triacylglycerols in adipose tissue and other organs results in obesity and other health problems such as cardiovascular disease, fatty liver, and diabetes.
Multiomics in Type 1 Diabetes
Combined transcriptomic, proteomic, lipidomic, & metabolomic analyses can characterize the molecular basis of diabetes.
TAG lipidomics analysis with
|Structural details||species level|
|Variants identified||> 250|
|Device||Q Exactive Orbitrap (280.000 Res)|
|Delivery time||2-6 weeks|
|Lipidomics data||pmol & mol%|
TAG, DAG, PA, PC, PE, PG, PI, PS, CE, SM
2Blood Basic includes:
TAG, DAG, PC, PE, PI, LPC, LPE, Cer, Chol, CE, PC O-, PE O-, SM
TAG, DAG, Chol, CE, NdS, NS, NP, NH, AdS, AS, AP, AH, EOdS, EOS, EOP, EOH
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