Sphingosine

We provide MS-based lipid analysis of Sph sphingolipids in a variety of sample types and deliver results in six or less weeks.
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Details

Sphingolipids
Lipid Category
Sphingoid Bases
Lipid Group
Sphingosine
Lipid Class

About the structure and biological function of Sph

What is the structure of Sphingosine?

Sphingosines (sphing-4-enines, sphingenines, D-erythro-sphingosines, or Sph) belong to the group of sphingoid bases within the sphingolipids. Their structure consists of an amino alcohol with a monounsaturated hydrocarbon chain.

What is the function of Sphingosine?

Sphingosines are the most abundant sphingoid bases in sphingolipids of animals and serve an important biological role as biosynthetic precursor to sphingosine-phosphates. As free sphingosines, they interact with specific receptors playing a crucial role in cellular signaling, including growth arrest and cell death. Further, sphingosines are involved in anti-infectious mechanisms against microbial diseases.

Sphingosine lipidomics analysis with Lipotype

Structural details
Variants identified
Approach
Method mass spectrometry
Device
Quantification yes
Delivery time
Lipidomics data pmol & mol%
Figures yes

Example Structure
Sph

An example for the molecular structure of sphingosine, specifically SPB 18:1;O2.

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Sph
analysis?

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Lipid Navigator

Categories

Fatty AcylsGlycerolipidsPhospholipidsSphingolipidsSterol LipidsPrenol Lipids

Groups

Fatty AcidsFatty AldehydesFatty EstersFatty AmidesHeptadecanoidsOctadecanoidsEicosanoidsDocosanoidsGlycerol EstersEster PhospholipidsEther PhospholipidsDiphospha­tidyl­glycerolsCDP-GlycerolsSphingoid BasesCeramide LipidsCerebrosidesDiglycosyl­ceramidesPhospho­sphingolipidsGangliosidesGlobosidesSulfoglyco­sphingolipidsCholesterol LipidsErgosterol LipidsIsoprenoidsQuinones

Classes

FFABCFASCFAMCFALCFAVLCFAoxiFALWECARNAEoxiHTrEoxiOMEoxiODEoxiOTrEPgdLTTXLXIsoPRvEoxiEDEoxiETrEoxiETEoxiEPEMaRRvDPDoxiDPAoxiDHATAGDAGMAGPAPCPEPGPIPSLPALPCLPELPGLPILPSBMPPC O-PE O-LPC O-LPE O-CLCDP-DAGSphdhSphSphPdhSphPGlcSphGalSphCerCerPdhCerdoxCerEOdSEOSEOPEOHNdSNSNPNHAdSASAPAHHexCerGlcCerGalCerDiHexCerLacCerSMCerPEIPCMIPCM(IP)2CGM1GM2GM3GM4GD1GD2GD3GT1GT2GT3GQ1Gb3Gb4SulfCholCEoxiCholLanoDesmLathErgEEC10TC15TSqeoxiSqeUQ
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